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Autor:
Félicie Sherer, Serge Goldman, Gaetan Van Simaeys, Amelie Castiaux, Benjamin Bondue, Celine Mathey, Dominique Egrise, Simon Lacroix, François Huaux, Gilles Doumont
Publikováno v:
Respiratory Research
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Respiratory research, 20 (1
Respiratory research, Vol. 20, no. 1, p. 10 (2019)
Respiratory Research, Vol 20, Iss 1, Pp 1-11 (2019)
Respiratory research, 20 (1
Respiratory research, Vol. 20, no. 1, p. 10 (2019)
Background: Idiopathic pulmonary fibrosis (IPF) is characterized by a progressive and irreversible respiratory failure. Non-invasive markers of disease activity are essential for prognosis and evaluation of early response to anti-fibrotic treatments.
Autor:
Roger R. Beerli, Špíšek Radek, Alexander Yermanos, Ulrike Menzel, Rémy Gebleux, Manfred Briendl, Fabian I. Wolter, Lucia D'Amico, Melanie Buchi, Sai T. Reddy, Philipp Müller, Ulrike Haessler, Iva Truxova, Alfred Zippelius, Abhishek S. Kashyap, Tatjana Vlajnic, Tamara Hell, Ulf Grawunder, Michael Prummer
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 7 (1)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Journal for ImmunoTherapy of Cancer, 7 (1)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Increasing evidence suggests that antibody-drug conjugates (ADCs) can enhance anti-tumor immunity and improve clinical outcome. Here, we elucidate the therapeutic efficacy and immune-mediated mechanisms of a novel HER2-targeting ADC bearing a potent
Autor:
Hyeoung-Joon Kim, Jae-Sook Ahn, Deok-Hwan Yang, Seo-Yeon Ahn, Sung-Hoon Jung, Je-Jung Lee, Seung-Yeon Jung, Ga-Young Song
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Background For successful autologous stem cell transplantation, the collection of a sufficient number of hematopoietic stem cells after induction therapy is essential for transplant candidates with multiple myeloma (MM). Methods In this study, we com
Autor:
Shiv K. Singh, Derrick Broka, Benjamin Atwell, Robert Kupp, Joyce A. Schroeder, Thomas Bunch, Sabrina Maisel, Shwetal Mehta
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Journal of Translational Medicine
Journal of Translational Medicine
Background The human epidermal growth factor receptor (HER) family of transmembrane tyrosine kinases is overexpressed and correlates with poor prognosis and decreased survival in many cancers. The receptor family has been therapeutically targeted, ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d5df4319a881475892b42e14b98db3
http://resolver.sub.uni-goettingen.de/purl?gs-1/16198
http://resolver.sub.uni-goettingen.de/purl?gs-1/16198
Autor:
Hui Wang, Zheyu Hu, Jing Li, Xuefeng Xia, Qiongzhi He, Yikai Wang, Quchang Ouyang, Jingyu Liu
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Background Among breast cancer (BC) patients, near 40% are post-menopause, and 70%–80% are hormone receptor (HR)-positive. About 30%–40% BC patients who are diagnosed as invasive carcinoma HR-positive BC would eventually develop metastatic breast
Autor:
Federico Bianciardi, Marialuisa Framarino-dei-Malatesta, Azzurra Ligato, Annalisa Chiarito, Irene Pecorella, Marco Fiorelli, Giuseppe Naso
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Background Unilateral or bilateral metastases to extraocular muscles are very rare in breast cancer. Case presentation We describe a case of inferior rectus extraocular muscle involved by ductal luminal B/Her-2 neu negative breast cancer, observed in
Autor:
Gloria Bellin, Gianluigi Zaza, Amedeo Carraro, Valentina Masola, Lorenzo Signorini, P Violi, Simona Granata, Maurizio Onisto, Giovanni Gambaro, Antonio Lupo, Umberto Tedeschi
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Background The epithelial to mesenchymal transition (EMT) is a multi-factorial biological mechanism involved in renal and hepatic fibrosis and the IL-1 beta has been assumed as a mediator of this process although data are not exhaustive. Therefore, t
Publikováno v:
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-4 (2019)
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-4 (2019)
We report a male with longstanding warts who presented with severe West Nile virus encephalitis (WNVE) and recovered after interferon alfa-2b and intravenous immunoglobulin. He was later found to have GATA2 deficiency and underwent successful hematop
Autor:
Elisabetta Buscarini, Luisa Maria Botella, Urban Geisthoff, Anette D. Kjeldsen, Hans Jurgen Mager, Fabio Pagella, Patrizia Suppressa, Roberto Zarrabeitia, Sophie Dupuis-Girod, Claire L. Shovlin, on behalf of VASCERN-HHT
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-14 (2019)
Buscarini, E, Botella, L M, Geisthoff, U, Kjeldsen, A D, Mager, H J, Pagella, F, Suppressa, P, Zarrabeitia, R, Dupuis-Girod, S, Shovlin, C L & on behalf of VASCERN-HHT 2019, ' Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia ', Orphanet Journal of Rare Diseases, vol. 14, 28 . https://doi.org/10.1186/s13023-018-0982-4
Orphanet Journal of Rare Diseases
instname
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-14 (2019)
Buscarini, E, Botella, L M, Geisthoff, U, Kjeldsen, A D, Mager, H J, Pagella, F, Suppressa, P, Zarrabeitia, R, Dupuis-Girod, S, Shovlin, C L & on behalf of VASCERN-HHT 2019, ' Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia ', Orphanet Journal of Rare Diseases, vol. 14, 28 . https://doi.org/10.1186/s13023-018-0982-4
Orphanet Journal of Rare Diseases
[Background] Hereditary hemorrhagic telangiectasia (HHT) is a multisystemic inherited vascular dysplasia that leads to nosebleeds and visceral arteriovenous malformations (AVMs). Anti-angiogenic drugs thalidomide and bevacizumab have been increasingl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c420f321730820d8a6f67fa5fe41daf5
http://hdl.handle.net/10044/1/67482
http://hdl.handle.net/10044/1/67482
Autor:
Ryosuke Motohashi, Osamu Kotake, Masahiko Shimura, Kanako Yasuda, Hiroshi Goto, Hidetaka Noma
Publikováno v:
Journal of Inflammation (London, England)
Journal of Inflammation, Vol 15, Iss 1, Pp 1-6 (2018)
Journal of Inflammation, Vol 15, Iss 1, Pp 1-6 (2018)
Background Intravitreal ranibizumab injection (IRI) is effective for patients with exudative age-related macular degeneration (AMD) and decreases intraocular levels of vascular endothelial growth factor (VEGF), but VEGF receptor intraocular dynamics