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Autor:
Lucas J. Cunningham, Frank T. Aboagye, Suzy J. Campbell, Buhari A. Hamidu, Samuel Armoo, Emily R. Adams, Freda K. Boampong, J. Russell Stothard, Mike Y. Osei-Atweneboana
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Infectious Diseases
BMC Infectious Diseases
Background In Ghana, pre-school-aged children (PSAC) are at risk of intestinal schistosomiasis and are living in need of praziquantel treatment. To better assess the infection burden within this vulnerable demographic group, we have provided a compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a857b09306b4f852aa6a87d38743d5
https://archive.lstmed.ac.uk/14382/1/Armoo.pdf
https://archive.lstmed.ac.uk/14382/1/Armoo.pdf
Autor:
Saranya Auparakkitanon, Tospon Lertwattanachai, Preecha Montakantikul, Pitchaya Dilokpattanamongkol, Viratch Tangsujaritvijit, Jetjamnong Sueajai, Pitsucha Sanguanwit
Publikováno v:
Journal of Intensive Care
Journal of Intensive Care, Vol 8, Iss 1, Pp 1-10 (2020)
Journal of Intensive Care, Vol 8, Iss 1, Pp 1-10 (2020)
Background Appropriate antimicrobial dosing is challenging because of changes in pharmacokinetics (PK) parameters and an increase in multidrug-resistant (MDR) organisms in critically ill patients. This study aimed to evaluate the effects of an empiri
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Background Breast cancer treatment is tailored to the specific cancer subtype. Often, systemic treatment is given prior to surgery. Chemotherapy induces significant endoplasmic reticulum (ER) stress-mediated cell death and upregulation of 78-kDa gluc
Autor:
Michelle P. Kallis, Brandon Blank, Marc Symons, Caroline Maloney, Samuel Z. Soffer, Bettie M. Steinberg
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Background Osteosarcoma is a highly metastatic primary bone tumor that predominantly affects adolescents and young adults. A mainstay of treatment in osteosarcoma is removal of the primary tumor. However, surgical excision itself has been implicated
Autor:
Seon Yoo Kim, Jae Chul Pyun, Jisu Kim, Hae Yong Ko, Jong Sook Lee, Yusun Park, Hanhee Jo, Misu Lee, Kyung Sik Kim, Mijin Yun, Jee In Chung, Tae Hun Kim
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Background Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide. The only drug currently approved for clinical use in the treatment of advanced HCC is sorafenib. However, many patients with HCC show reduced sensitivi
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-4 (2020)
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-4 (2020)
Background Campylobacter jejuni is a motile, gram-negative rod known for causing self-limiting enterocolitis while rarely causing extraintestinal infections. We report the first case of a patient with Campylobacter jejuni osteomyelitis in both femora
Autor:
Jane Holmes, Leena Elhussein, Claire Brooks, Tim Maughan, Corran Roberts, Tim Coutts, S.M. Ng, Nicholas F. Brown, Peter Hoskin, Paul Mulholland, Sarah P. Blagden
Publikováno v:
BMC Cancer
Brown, N F, Ng, S M, Brooks, C, Coutts, T, Holmes, J, Roberts, C, Elhussein, L, Hoskin, P, Maughan, T, Blagden, S & Mulholland, P 2020, ' A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma : The Ipi-Glio trial protocol ', BMC Cancer, vol. 20, no. 1, 198 . https://doi.org/10.1186/s12885-020-6624-y
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
Brown, N F, Ng, S M, Brooks, C, Coutts, T, Holmes, J, Roberts, C, Elhussein, L, Hoskin, P, Maughan, T, Blagden, S & Mulholland, P 2020, ' A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma : The Ipi-Glio trial protocol ', BMC Cancer, vol. 20, no. 1, 198 . https://doi.org/10.1186/s12885-020-6624-y
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
BackgroundMedian survival for patients with glioblastoma is less than a year. Standard treatment consists of surgical debulking if feasible followed by temozolomide chemo-radiotherapy. The immune checkpoint inhibitor ipilimumab targets cytotoxic T-ly
Autor:
Ryota Tamura, Yukina Morimoto, Kenzo Kosugi, Mizuto Sato, Yumiko Oishi, Ryo Ueda, Ryogo Kikuchi, Hideaki Nagashima, Tetsuro Hikichi, Shinobu Noji, Yutaka Kawakami, Hikaru Sasaki, Kazunari Yoshida, Masahiro Toda
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Background The expression of vascular endothelial growth factor (VEGF)-A/ VAGF receptors (VEGFRs) signaling plays a pivotal role in the tumor angiogenesis and the development of the immunosuppressive tumor microenvironment in glioblastomas. We have p
Autor:
Maria Paola Canevini, Miriam Nella Savini, F. Cervi, Aglaia Vignoli, Alessia Mingarelli, Rosa Maria Alfano, Angela Peron, F. La Briola
Publikováno v:
Italian Journal of Pediatrics
Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-10 (2020)
Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-10 (2020)
Background Seizures in individuals affected by tuberous sclerosis complex (TSC) commonly develop in the first year of life, are often preceded by a progressive deterioration of the electroencephalogram (EEG), and likely influence developmental outcom
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)
Background Dabrafenib and trametinib combination therapy is approved for the treatment of patients with BRAF V600E positive tumors including melanoma and lung cancer. The effect of BRAF and MEK inhibitors on the immune system is not fully understood