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Autor:
Luca Mologni, Carlo Gambacorti-Passerini, Rosalind H. Gunby, Elisa Sala, Carmen J Tartari, Miriam Puttini
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 7:594-611
Deregulated activation of protein tyrosine kinases (PTKs) is a frequent event underlying malignant transformation in many types of cancer. The formation of oncogenic fusion tyrosine kinases (FTKs) resulting from genomic rearrangements, represents a c