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Publikováno v:
Current Molecular Medicine. 22:491-505
Exosomal vesicles enclose and carry a broad range of biological molecules, such as nucleic acids, lipids, and proteins, and transfer them between cells. In cancer, cells being mentioned could be neighbors in the same tumor microenvironment communicat
Autor:
Sukhes Mukherjee, Suman Kumar Ray
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1257-1271
Tissues are progressively molded by bidirectional correspondence between denizen cells and extracellular matrix (ECM) via cell-matrix connections along with ECM remodeling. The composition and association of ECM are spatiotemporally directed to contr
Publikováno v:
Current Protein & Peptide Science. 23:158-165
Abstract: Cancer is fundamentally a disease of perturbed genes. Although many mutations can be marked in the genome of cancer or a transformed cell, the initiation and progression are driven by only a few mutational events, viz., driver mutations tha
Publikováno v:
Current Molecular Medicine. 22:151-164
Liver fibrosis is one of the leading causes for cirrhotic liver disease and the lack of therapies to treat fibrotic liver is a major concern. Liver fibrosis is mainly occurred by activation of hepatic stellate cells and some stem cell therapies had p
Autor:
Fatima Akram, Ikram ul Haq, Zuriat Jabbar, Rabia Akram, Ali Nawaz, Amna Aqeel, Noman Atique, Zeeshan Ahmed
Publikováno v:
Current Protein & Peptide Science. 22:599-619
Background: MicroRNAs (miRNA) belong to the substantial class of posttranscriptional gene regulators with decisive functions in typical cellular and disease progressions. They are short RNA molecules that are not translated into proteins but bind to
Publikováno v:
Current Protein & Peptide Science. 22:567-573
Background: Ovarian cancer is one of the leading causes of death worldwide. Polymers have low cytotoxicity and high functionalizability and are hence used for drug delivery systems, tissue engineering, and polymer therapeutics. In drug delivery syste
Publikováno v:
Current Protein & Peptide Science. 22:548-558
Post Translational Modification (PTM) is a process in which covalent addition of functional groups on protein occurs to maintain their structure, function and stability. Every PTM process in our living system occurs to enhance the functional diversit
Publikováno v:
Current Medicinal Chemistry. 28:8480-8495
The oxidative stress response is critical for malignant cells. It plays a dual role by helping cancer cells survive and proliferate but also causing apoptosis and apoptosis-- like cell death. The oxidative stress response is characterized by tight re
Publikováno v:
Current Protein & Peptide Science. 22:831-847
Soybean has become an important world commodity because of its low price, good nutritional value and recognized functional health benefits in recent years. β-conglycinin is one of the major storage proteins in soybean. It has captured a growing inte
Autor:
Irais Castillo Maldonado, Maira Fernanda Zambrano Carrillo, Dealmy Delgadillo Guzmán, Laura Ernestina Barragán Ledezma Barragán Ledezma, Martha Angelica Quintanar Escorza, Eva Ortega Freyre, Alfredo Tellez Valencia
Publikováno v:
Current Protein & Peptide Science. 22:890-897
Exposure to organophosphorus pesticides is an important public health issue due to a large number of occupationally exposed populations, as well as their effects mainly at the level of the nervous, reproductive, and immune systems. It has been report