Zobrazeno 61 - 70
of 379
pro vyhledávání: ''
Autor:
Mohammad Davoodzadeh Gholami, Majid Khoshmirsafa, Mohammad Hossein Kazemi, Sahel Heidari, Elaheh Safari, Gholam A. Kardar, Reza Falak, Nader Tajik, Amir-Hassan Zarnani
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 14:158-169
Background: Epithelial-to-Mesenchymal Transition (EMT) is necessary for metastasis. Zinc- finger domain-containing transcription factors, especially Snail1, bind to E-box motifs and play a crucial role in the induction and regulation of EMT. Objectiv
Publikováno v:
Current Protein & Peptide Science. 20:789-798
Intracranial aneurysms (IA) are a huge threat to human health, with a global incidence rate of 0.65–8.4%. Although the microsurgical and interventional techniques have made profound progression in treating IA, the relatively high rate of complicati
Autor:
Yu-Jen Tseng, Wei Ma, Nuo Xu, Sheng-Di Wu, Yufeng Liu, Shuqiang Weng, Ling Dong, Harry L.A. Janssen
Publikováno v:
Current Protein & Peptide Science. 20:817-822
Autophagy entails the removal of dysfunctional components to maintain cellular homeostasis. Over the years, studies of autophagy demonstrated its complex physiological and pathological roles in the liver. Apart from regulation of normal metabolic fun
Autor:
Shixiu Feng, Xiaoxia Wang, Wenjian Zhang, Huazhi Ma, Chengfang Tang, Wenyu Ma, Xuanying Wang, Xiaoting Wu, Yanbin Dong, Zehong Yang, Zhihao Li, Yong Gao, Fenglian Zhang, Li-Ping Tian, Huiling Hu
Publikováno v:
Current Protein & Peptide Science. 20:683-689
Weaning is a critical period for the growth and development of mammals, in which various physiological and biochemical indicators of the body have undergone great changes. The development, differentiation, and maturation of the nervous system are reg
Autor:
Zehong Yang, Bo Cheng, Yanwu Li, Aiping Wang, Yong Gao, Xi Chen, Weihang Gao, Wenfeng Guo, Nannan Sun, Zhibin Cheng, Song Deng, Jiali Li, Yanbin Dong, Wentao Duan, Huiling Hu
Publikováno v:
Current Protein & Peptide Science. 20:690-695
Weaning is a stressful event associated with gastrointestinal disorders and increased disease susceptibility. Many studies have reported the changes that happened in the gut of various mammals such as pigs and rats after weaning. These findings sugge
Autor:
Inger Lauritzen, Raphaëlle Pardossi-Piquard, Frédéric Checler, Anaïs Bécot, Alexandre Bourgeois
Publikováno v:
Current Alzheimer Research
Current Alzheimer Research, Bentham Science Publishers, 2019, 16 (5), pp.453-457. ⟨10.2174/1567205016666190325092841⟩
Current Alzheimer Research, Bentham Science Publishers, 2019, 16 (5), pp.453-457. ⟨10.2174/1567205016666190325092841⟩
Background: Alzheimer’s disease (AD) is associated with extracellular accumulation and aggregation of amyloid β (Aβ) peptides ultimately seeding in senile plaques. Recent data show that their direct precursor C99 (βCTF) also accumulates in AD-af
Publikováno v:
Current Protein & Peptide Science. 20:536-546
Several molecular mechanisms are involved in the regulation of skeletal muscle function. Among them, mitochondrial activity can be identified. The mitochondria is an important and essential organelle in the skeletal muscle that is involved in metabol
Autor:
Junjie Wang, Kaishun Xia, Yitian Wang, Jian Zhu, Yuluan Huang, Wei Yu, Fangcai Li, Bing Liu, Huimin Tao, Chengzhen Liang
Publikováno v:
Current Stem Cell Research & Therapy. 14:259-267
Background:Long suspected as transcriptional noise, recently recognized, long non-coding RNAs (lncRNAs) are emerging as an indicator, biomarker and therapy target in the physiologic and pathologic process. Mesenchymal stem cells and embryonic stem ce
Publikováno v:
Current Pharmaceutical Design. 24:5252-5267
Redox homeostasis is important for the maintenance of cell survival. Under physiological conditions, redox system works in a balance and involves activation of many signaling molecules. Regulation of redox balance via signaling molecules is achieved
Publikováno v:
Current Protein & Peptide Science. 20:304-315
Triosephosphate isomerase is the fifth enzyme in glycolysis and its canonical function is the reversible isomerization of glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Within the last decade multiple other functions, that may not necessa