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Autor:
Konstantinos A. Papathanasiou, Mauro Gitto, Gianluigi Condorelli, Spyridon Deftereos, Bernhard Reimers, Giulio G. Stefanini, Dimitrios A. Vrachatis
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 20:90-102
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of anti-diabetic agents that block the reabsorption of glucose in the proximal convoluted tubule of the nephron, thereby contributing to glycosuria and lowering blood glucose levels. SGLT2
Autor:
Nikos Tsolakos, Leonidas G. Alexopoulos, Nikoleta Karampetsou, Despoina Perrea, Ioannis A. Chloroyiannis, Aggeliki Minia, Konstantinos Kontzoglou, Evanthia Bletsa, Paulos Patapis, Aspasia Tzani, Ilias P. Doulamis, Dimitris Tousoulis, Vaia Pliaka, Evangelos Oikonomou
Publikováno v:
Current Vascular Pharmacology. 20:87-93
Background: Epicardial adipose tissue (EAT) surrounds the epicardium and can mediate harmful effects related to coronary artery disease (CAD). Objective: We explored the regional differences between adipose stores surrounding diseased and non-disease
Publikováno v:
The Open Cardiovascular Medicine Journal. 15:29-37
Background: Inflammation plays a pivotal role in the pathogenesis of In-Stent Restenosis (ISR). High sensitivity C-reactive protein (hsCRP) is positively associated with major cardiovascular events. Aim: We aimed to investigate the hsCRP inflammatory
Autor:
Rodgers M Manganyi, Chima K P Ofoegbu
Publikováno v:
Current Cardiology Reviews. 18
Off-pump Coronary Artery Bypass Grafting (OPCAB) experienced a resurgence in the 1980s -2000s and developed steadily with improvement of the instrumentation and techniques. However questions about graft patency and long-term survival of OPCAB patient
Publikováno v:
Current Cardiology Reviews
Atrial conduction disorders result from impaired propagation of cardiac impulses from the sinoatrial node through the atrial conduction pathways. Disorders affecting interatrial conduction alter P-wave characteristics on the surface electrocardiogram
Autor:
Michael Doumas, Konstantinos Imprialos, Konstantinos Koutsampasopoulos, Athanasios J. Manolis
Publikováno v:
Current Vascular Pharmacology. 19:301-312
Background: Erectile dysfunction (ED) is a major health problem that affects a significant proportion of the general population, and its prevalence is even higher in patients with CV risk factors and/or disease. ED and cardiovascular (CV) disease sha
Autor:
Debabrata Mukherjee, Angelica Lehker
Publikováno v:
Current Vascular Pharmacology. 19:280-284
The association between the presence of coronary artery calcium (CAC) and the risk of coronary artery disease (CAD) has been appreciated for decades. In this review, we critically appraise the role of CAC based on computerized tomography in contempor
Publikováno v:
Current Cardiology Reviews
Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion.\ud \ud Flow through these channels is driven by a pressure gradient between the donor and occluded artery.\ud \ud Concomitant with increased collateral
Publikováno v:
Current Cardiology Reviews
Like other adipokines, omentin-1 is secreted from visceral adipose tissue and plays a vital role in the development of chronic inflammatory diseases, including cardiovascular events. Recent studies have shown that circulating omentin-1 levels are ass
Autor:
Federico Marin, Giovanni Luigi De Maria, Flavio Ribichini, Rafail A. Kotronias, Dimitrios Terentes-Printzios, Adrian P. Banning, Roberto Scarsini
Publikováno v:
Current Cardiology Reviews. 18
Invasive assessment of coronary physiology has radically changed the paradigm of myocardial revascularization in patients with coronary artery disease. Despite the prognostic improvement associated with ischemia-driven revascularization strategy, fun