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Autor:
Debabrata Mukherjee, Angelica Lehker
Publikováno v:
Current Vascular Pharmacology. 19:280-284
The association between the presence of coronary artery calcium (CAC) and the risk of coronary artery disease (CAD) has been appreciated for decades. In this review, we critically appraise the role of CAC based on computerized tomography in contempor
Publikováno v:
Current Vascular Pharmacology. 15:59-65
Objective: To evaluate the epidemiological and morphological characteristics of coronary plaque in diabetic patients with symptomatic coronary heart disease (CHD) by dual-source computed tomography (DSCT). Materials and Methods: From June 2013 to Dec
Autor:
Chiara Cavallino, Alessandro Lupi, Roberta Rosso, Gioel Gabrio Secco, Angelo S. Bongo, Andrea Rognoni
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 13:4-9
Heart rate is a fundamental determinant of cardiac oxygen consumption and plays a pivotal role in the pathophysiology of chronic stable angina (CSA). Ivabradine selectively and specifically inhibits the sino-atrial If current, slowing selectively hea
Autor:
Chiara Cavallino, Gioel Gabrio Secco, Francesco Rametta, Federico Nardi, Manuela Facchini, Angelo S. Bongo, Andrea Rognoni, Roberta Rosso, Alessia Veia, Sara Bacchini, Alessandro Lupi
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 13:10-13
Cardiovascular diseases and in particular coronary atherosclerotic disease are the leading cause of mortality and morbidity in the industrialized countries. Coronary atherosclerosis has been recognized for over a century and it was the subject of var
Autor:
Maurizio Lazzero, Andrea Rognoni, Gioel Gabrio Secco, Alessandro Lupi, Chiara Cavallino, Mara Sansa, Angelo S. Bongo
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 9:106-112
Coronary artery diseases continue to be the most common causes of mortality and morbidity in the industrialized world, especially in the setting of acute myocardial infarction. Platelets play a crucial role in thrombosis and haemostasis, which can be
Autor:
Raffaele De Caterina, Ugo Limbruno
Publikováno v:
Current Vascular Pharmacology. 1:321-328
Routinely used iodinated contrast media have complex vasomotor effects on several arterial districts. All classes of iodinated radiographic contrast media are vasoactive, with iso-osmolar dimers inducing the smallest changes in vascular tone. The mec
Autor:
Paul Schoenhagen, Steven E. Nissen
Publikováno v:
Current Drug Target -Cardiovascular & Hematological Disorders. 3:218-226
Coronary artery disease (CAD) represents the major cause of mortality in North America and Western Europe. Most acute coronary events, including myocardial infarction (MI) and sudden cardiac death, are initiated by the sudden rupture of mildly stenot