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Autor:
Zemene Demelash Kifle, Agumas Alemu Alehegn, Engidaw Fentahun Enyew, Baye Yrga Adugna, Abebe Basazn Mekuria
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 20:67-74
Background: Diabetes mellitus is one of the major and common metabolic and chronic disorders in the world. Several medicinal plants have been used globally for the management of diabetes mellitus. The current study aimed to study the antihyperglycemi
Autor:
Rosa Diaz Campillejo, Guillermo Gervasini, J. Villa, Nicolás Roberto Robles, Elena Garcia de Vinuesa, Julian Valladares
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 19:93-97
Background and Aims: Anemia is a common complication of heart failure and Chronic Kidney Disease (CKD). Sacubitril-valsartan is a novel therapy for the treatment of chronic Heart Failure with a reduced Ejection Fraction (HFrEF). We have evaluated the
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 19:62-71
Aims: The study aimed to evaluate the antihyperlipidemic and antioxidant activities of Matricaria pubescens. Background: Matricaria pubescens (Desf.) Shultz belongs to Asteraceae family and it is commonly used traditionally for handling diabetes mell
Publikováno v:
Current Vascular Pharmacology. 19:390-397
Background: Statins are the mainstay of treatment for low-density lipoprotein cholesterol (LDL-C) lowering, however, some patients cannot tolerate statins because of adverse effects. Ezetimibe and proprotein convertase subtilisin/kexin type 9 inhibit
Publikováno v:
Cardiovascular & Hematological Disorders-Drug Targets. 20:297-304
Aims: The study aimed to investigate the antihyperglycemic activity of Matricaria pubescens. Background: Matricaria pubescens (Def). Shultz (Asteraceae) is commonly used traditionally for the treatment of diabetes in Morocco. Objective: The present i
Publikováno v:
Cardiovascular & Hematological Disorders-Drug Targets. 19:176-182
Background:Curcumin is the one of the main phenolic ingredients in curcuma species rhizome. Curcuma species have traditionally been used for the treatment of diabetes, cardiovascular, and renal diseases.Methods:The present study was designed to revie
Autor:
Simon W. Rabkin
Publikováno v:
Current Vascular Pharmacology. 14:514-522
Background Aortic aneurysms (AAs) are without effective pharmacologic therapy, in clinical usage, in part because of the limited understanding of factors leading to AA development. Objective The objectives of this study were to examine the evidence t
Autor:
Vasilios G. Athyros
Publikováno v:
The Open Cardiovascular Medicine Journal. 9:73-77
Familial hypercholesterolaemia (FH) is the most common inherited monogenic lipid disorder. It is caused by mutations of genes related to low density lipoprotein (LDL) receptors, apolipoprotein B or proprotein convertase subtilisin/kexin type 9 (PCSK9
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry
Background: Thiopurine S-methyltransferase (TPMT) enzyme metabolizes thiopurine drugs which are widely used in various disciplines as well as in leukemias. Individual enzyme activity varies depending on the genetic polymorphisms of TPMT gene located
Publikováno v:
Recent Patents on Cardiovascular Drug Discovery. 9:28-37
Heart Failure (HF) is a progressive and fatal disorder, which ranks among the major public health problems in Brazil and worldwide. However, survival for patients who developed the syndrome after myocardial infarction (MI) enhanced significantly, as