Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jingfa Zhang"'
Autor:
Shuai Yang, Haipei Yao, Jingfa Zhang, Hui Li, Yao Zhang, Fang Wang, Huiqian Bao, Haiying Jin, Guo-Tong Xu
Publikováno v:
Investigative Opthalmology & Visual Science. 60:5104
Purpose Cell-cell contact in retinal pigment epithelium (RPE) involves adherent junctions, gap junctions, and tight junctions, which are primarily composed by E-cadherin, zona occludens 1 (ZO-1), and connexin 43, respectively. Here, we aimed to explo
Autor:
Guo-Tong Xu, Jing Ying Xu, Debasish Sinha, Limin Gu, Jingfa Zhang, Lixia Lu, Juan Wang, Haibin Tian, Furong Gao, Hua Xu, Weiye Li, Fang Wang, Guoxu Xu
Publikováno v:
Investigative Ophthalmology & Visual Science. 55:8208-8222
Purpose Retinal neuronal cell dysfunction and even cell death are associated with increased excitotoxic glutamate (Glu) level in the retina. Our aim was to study a causative mechanism of Glu on retinal cell death and explore the neuroprotective role
Autor:
Qian Yang, Lixia Lu, Hui Lou, Jingfa Zhang, Chen Sun, Fang Wang, Guoxu Xu, Daohuan Kang, Chaoyang Zhang, Guo-Tong Xu
Publikováno v:
Investigative Opthalmology & Visual Science. 56:8166
Purpose Zinc transporter 8 (ZnT8) was downregulated in hypoxic retina, which could be rescued by hypoxia-inducible factor-1α (HIF-1α) inhibition. Erythropoietin (EPO) protects retinal cells in diabetic rats through inhibiting HIF-1α as one of its
Autor:
Peng Shang, Chun-Chun Zhuge, Peng Li, Guo-Tong Xu, Weiye Li, Xiaoqing Liu, Fang Wang, Hua Xu, Zongyi Li, Lixia Lu, Jingfa Zhang, Jing-Ying Xu, Yanjun Lu, Ling Chen
Publikováno v:
Investigative Opthalmology & Visual Science. 55:4628
PURPOSE Oxidative stress-induced retinal pigment epithelium (RPE) senescence is one of the important factors in the pathogenesis of age-related macular degeneration (AMD). This study aimed to develop a new antisenescence-based intervention and clarif
Autor:
Shengfang Ge, Limei Zhang, Chuanyin Li, Zhiliang Wang, Ping Chen, Xiaolin Huang, Jingfa Zhang, Xianqun Fan, Yuting Yao, Xin Che
Publikováno v:
Investigative Opthalmology & Visual Science. 54:4964
Purpose We studied the mechanism by which complete posterior vitreous detachment by enzyme-induced vitreolysis alleviates the progression of diabetic retinopathy. Methods We enrolled 50 diabetic rats and 20 normal control rats in this study. The righ