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Autor:
Junichi Ikeda, Takashi Yoshida, Chisato Ohe, Hidefumi Kinoshita, Koji Tsuta, Haruyuki Ohsugi, Motohiko Sugi
Publikováno v:
Anticancer Research. 41:4577-4586
Background/aim Expression of programmed death ligand-1 (PD-L1) is associated with poor prognosis in renal cell carcinoma (RCC). Although a new antibody clone for immunohistochemical assay, 73-10, has shown greater sensitivity than other assays (28-8,
Autor:
Toshifumi Wakai, Takashi Kobayashi, Hitoshi Kameyama, Yuki Hirose, Kizuki Yuza, Kohei Miura, Masayuki Nagahashi, Hiroshi Ichikawa, Mae Nakano, Yoshifumi Shimada, Jun Sakata
Publikováno v:
Anticancer Research. 41:1563-1570
Background/aim This study aimed to evaluate how NAD(P)H: quinone oxidoreductase-1 (NQO1) affects survival after hepatectomy in patients with colorectal liver metastasis (CRLM). Patients and methods A retrospective analysis was conducted of 88 consecu
Autor:
Kazumasa Fukuda, Tomohiko Nishi, Hiroya Takeuchi, Rieko Nakamura, Masazumi Inoue, Sachiko Matsuda, Hirofumi Kawakubo, Norihito Wada, Tsunehiro Takahashi, Yuko Kitagawa
Publikováno v:
Anticancer Research. 41:783-794
BACKGROUND/AIM The inflammatory cytokine IL-8 and its receptor CXCR2 are key signalling pathway molecules in cancer development. We hypothesized that IL-8/CXCR2 signalling promotes tumour progression in oesophageal squamous cell carcinoma (ESCC) pati
Publikováno v:
Anticancer Research. 41:101-111
Background/aim The expression of tumor-associated programmed death-ligand 1 (PD-L1) predicts clinical responses to PD-1-directed immunotherapy. The expression levels of PD-L2, another PD-1 ligand, and its relationship with responses to PD-1-targeting
Autor:
Michiel A. J. van de Sande, Jozef Michielsen, Sander Dijkstra, Veroniek M. van Praag, Thomas Schubert, Felix Shumelinsky, Annelies Van Beeck, Bilal Kapanci, Johan Somville, Dietmar Dammerer
Publikováno v:
Anticancer research, Vol. 40, no. 9, p. 5319-5325 (2020)
Anticancer research
Anticancer Research, 40(9), 5319-5325. INT INST ANTICANCER RESEARCH
Anticancer research
Anticancer Research, 40(9), 5319-5325. INT INST ANTICANCER RESEARCH
Aim: This study was interested in extremity leiomyosarcoma with focus on clinical outcome after surgery with or without adjuvant therapy. Patients and Methods: A retrospective case series of all patients with leiomyosarcoma, surgically treated betwee
Autor:
Natália Araújo, Susana Pereira, Filipa Fontes, Nuno Lunet, Samantha Morais, Teresa Dias, Mariana Brandão, Luisa Lopes-Conceição, Ana Rute Costa, Marina Borges
Publikováno v:
Anticancer Research. 40:1041-1048
Background/Aim: To quantify the association between a previous cancer diagnosis and healthcare use among breast cancer (BC) patients, and estimate five-year recurrence-free survival (RFS). Patients and Methods: Women with BC were classified according
Publikováno v:
Anticancer Research. 40:81-86
BACKGROUND/AIM Zinc finger protein ZKSCAN3 (ZNF306) is a promising oncogene candidate in colon, bladder, breast, uterine cervical, and prostate cancers. The present study aimed to investigate ZKSCAN3 protein expression in gastric carcinoma patient ti
Publikováno v:
Anticancer Research. 39:4947-4955
Background/aim Insulin-like growth factor II mRNA-binding protein 3 (IMP3) plays an important role in the adhesion, invasion, and metastasis of tumor cells. Although emerging evidence suggests that IMP3 promotes tumor progression in several malignanc
Publikováno v:
Anticancer Research. 39:4681-4685
BACKGROUND/AIM S100A8 is a chemoattractant known to be associated with metastatic niche formation. Herein, we evaluated the prognostic value of S100A8 in patients with clear cell renal cell carcinoma (CCRCC). MATERIALS AND METHODS A total of 152 CCRC
Autor:
Higashijima Jun, Kozo Yoshikawa, Daichi Ishikawa, Hideya Kashihara, Tumenjin Enkhbat, Takuya Tokunaga, Mitsuo Shimada, Chie Takasu, Masaaki Nishi
Publikováno v:
Anticancer Research. 38:3367-3373
Background/aim Programmed cell death protein 1 (PD-1)/ programmed cell death ligand 1(PD-L1) axis is associated with immune tolerance via inhibition of T cell activation. The aim of this study was to clarify the significance of PD-1 and PD-L1 express