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Autor:
Akihiro Ohmoto, Naoki Fukuda, Kazuhisa Toda, Hiroki Mitani, Naomi Hayashi, Kenji Nakano, Shunji Takahashi, Yasuyoshi Sato, Junichi Tomomatsu, Makiko Ono, Tetsuya Urasaki, Xiaofei Wang
Publikováno v:
Anticancer Research. 41:1683-1691
BACKGROUND/AIM Lenvatinib is standard therapy for radioiodine-refractory differentiated thyroid cancer (RR-DTC), although the optimal timing for starting treatment is still controversial. The aim of this study was to evaluate the prognostic impact of
Autor:
Paloma Lluch, Guadalupe Herrera, Pascual Medina, Joan Tosca, Salvador Lluch, Javier Navarrete-Navarro, Ana Sanahuja, Sherly Hernandez, Gloria Segarra, Laia Navarro
Publikováno v:
Anticancer Research. 40:6853-6861
Background/aim In chronic liver disease, various immune cell subsets exert pro or anti-tumour effects by releasing reactive oxygen and nitrogen species (ROS, RNS). Here, we evaluated the oxidative and nitrosative pattern in peripheral blood leukocyte
Autor:
Toshifumi Takahashi, Makiko Ueda, Shu Soeda, Takafumi Watanabe, Yuta Endo, Tetsu Sato, Hidekazu Nishigori, Norihito Kamo, Shigenori Furukawa, Shinji Nomura, Chikako Okabe, Keiya Fujimori, Kojima Manabu
Publikováno v:
Anticancer Research. 40:5263-5270
Background Treatment for platinum-resistant ovarian cancer is difficult and challenging because available chemotherapeutic agents only offer short survival improvements. The efficacy of re-treatment with platinum-based agents including nedaplatin for
Autor:
Marek Dudziński, Monika Długosz-Danecka, Małgorzata Wojciechowska, Michal Osowiecki, Elżbieta Iskierka-Jażdżewska, Weronika Piszczek, Jan Maciej Zaucha, Agnieszka Szymczyk, Edyta Subocz, Joanna Drozd-Sokołowska, Anna Waszczuk-Gajda, Beata Kumiega, Krzysztof Giannopoulos, Ryszard Wichary, Marek Hus, Bartosz Pula, Wojciech Jurczak, Tadeusz Robak, Bożena Katarzyna Budziszewska, Janusz Hałka, Wanda Knopinska-Posluszny, Krzysztof Jamroziak, Agnieszka Szeremet, Andrzej Pluta, Daria Zawirska, Paweł Steckiewicz, Jadwiga Hołojda, Ewa Lech-Marańda
Publikováno v:
Anticancer Research. 40:4059-4066
Background/aim To study the long-term clinical efficacy and tolerability of ibrutinib monotherapy in real-world relapsed and refractory chronic lymphocytic leukemia (RR-CLL) patients outside clinical trials. Patients and methods Clinical data of 171
Autor:
Mi Young Choi, Sang-Won Um, Ji-Ho Kim, Jin-Sik Bae, Jhingook Kim, Seong Keun Kim, Kyungjong Lee, Hong Kwan Kim, Seong Mi Moon, Seonwoo Kim, Hye Seon Lee, Sung-Hoon Lee, Byeong-Ho Jeong, Byung Hee Jeon, Hyukjung Kwon
Publikováno v:
Anticancer Research. 40:3435-3444
BACKGROUND/AIM Although it has been suggested that circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) might be used in a complementary manner in lung cancer diagnosis, limited confirmatory data are available. In this prospective study,
Autor:
Masatoshi Ishigami, Teiji Kuzuya, Yoji Ishizu, Takashi Honda, Mitsuhiro Fujishiro, Tetsuya Ishikawa, Takanori Ito
Publikováno v:
Anticancer Research. 40:2089-2093
Background/aim The outcomes of ramucirumab after lenvatinib failure for hepatocellular carcinoma (HCC) patients with alpha fetoprotein (AFP) levels of ≥400 ng/ml are unknown. Patients and methods Of 12 patients treated with ramucirumab after lenvat
Publikováno v:
Anticancer Research. 40:1605-1611
BACKGROUND/AIM The aim of this study was to clarify the risk benefits of folinic acid, fluorouracil, and irinotecan (FOLFIRI) plus ramucirumab (F-RAM) as third-line and later-line treatment for metastatic colorectal cancer (mCRC). PATIENTS AND METHOD
Publikováno v:
Anticancer Research. 40:873-880
The acidic tumor microenvironment is associated both with the progression and drug resistance of cancer. We aimed to investigate the effects of alkalization therapy performed concurrently with chemotherapy on the survival of advanced pancreatic cance
Autor:
Masahiko Koike, Kouichi Sawaki, Kenji Omae, Masamichi Hayashi, Dai Shimizu, Shunsuke Nakamura, Suguru Yamada, Goro Nakayama, Norifumi Hattori, Mitsuro Kanda, Chie Tanaka, Yasuhiro Kodera
Publikováno v:
Cancer Genomics Proteomics
Background Despite advances in our understanding on the pathogenesis of gastric cancer (GC), patients face a poor prognosis. To improve clinical outcomes, effective approaches to diagnosis and treatment employing new diagnostic biomarkers are require
Autor:
Takurou Ushigome, Takahiro Kitagawa, Katsuhiko Yanaga, Katsuhito Suwa, Marie Aizawa, Shunjin Ryu, Tomoyoshi Okamoto, Ken Eto
Publikováno v:
Anticancer Research. 40:373-377
Aim In colorectal cancer surgery, the efficacy of intestinal blood flow evaluation with the indocyanine green (ICG) fluorescence method using the VISERA ELITE2 system was investigated. Patients and methods Participants in this study comprised 50 pati