Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Pascal Chanez"'
Autor:
Charles Pilette, Chantal Fregimilicka, Bruno Detry, Sophie Gohy, Caroline Bouzin, Sébastien Dupasquier, Marylène Lecocq, Delphine Gras, Maha Zohra Ladjemi, Céline Garulli, Pascal Chanez
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:1396-1409
Rationale: Asthma is associated with increased lung IgE production, but whether the secretory IgA system is affected in this disease remains unknown.Objectives: We explored mucosal IgA transport in...
Autor:
Michel Laviolette, Delphine Gras, Simon Martel, Ikhlass Haj Salem, Philippe Joubert, Noel Lampron, Pascal Chanez, Louis-Philippe Boulet, Jamila Chakir, Krystelle Godbout
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 199:536-538
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, Vol. 198, no. 9, p. 1236-1238 (2018)
From the Authors: We thank Dr. Upham for his interest and comments on our article about pIgR/SC (polymeric immunoglobulin receptor/secretory component) in asthma (1). First, although our data indeed show that bronchoepithelial pIgR immunostaining is
Autor:
Michel Aubier, Gabriel Thabut, Marina Pretolani, Fatima Hamidi, Camille Taillé, Dominique Knap, Pascal Chanez, Marie-Pierre Debray, Marie-Christine Dombret
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 190:1452-1454
Autor:
Sally E, Wenzel, Peter J, Barnes, Eugene R, Bleecker, Jean, Bousquet, William, Busse, Sven-Erik, Dahlén, Stephen T, Holgate, Deborah A, Meyers, Klaus F, Rabe, Adam, Antczak, James, Baker, Ildiko, Horvath, Zsuzsanna, Mark, David, Bernstein, Edward, Kerwin, Rozsa, Schlenker-Herceg, Kim Hung, Lo, Rosemary, Watt, Elliot S, Barnathan, Pascal, Chanez, E H, Bel
Publikováno v:
American journal of respiratory and critical care medicine, 179(7), 549-558. American Thoracic Society
Rationale The treatment effect of golimumab, a human monoclonal antibody against tumor necrosis factor (TNF)-alpha, in severe persistent asthma is unknown. Objectives To assess the safety and efficacy of golimumab in a large population of patients wi
Autor:
Giovanni Bonsignore, Pascal Chanez, Antonio M. Vignola, Rosalia Gagliardo, Claire Gougat, Jean Bousquet, Giorgia Costanzo, Isabelle Vachier, Andreina Bruno, Marc Mathieu
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 168:1190-1198
The transcription factor nuclear factor-kappaB (NF-kappaB) is inactive when bound to its inhibitory protein IkappaBalpha. On cell stimulation with inflammatory signals, IkappaBalpha is phosphorylated by IkappaB kinases and subsequently degraded. Free
Autor:
Philippe Godard, Pascal Chanez, Alison M. Campbell, Jean Bousquet, Nathalie Carayol, Brigitte Mainprice, Isabelle Vachier
Publikováno v:
Scopus-Elsevier
Asthma is an inflammatory disease, and the epithelial mesenchymal unit appears to be of importance in regulating the disease mechanisms. Cell-cell adhesion plays an important role in tissue morphogenesis and homeostasis and is commonly mediated by ca
Autor:
Isabelle Vachier, Pascal Demoly, Pascal Chanez, Philippe Godard, Marc Mathieu, Giovanni Bonsignore, Rosalia Gagliardo, Antonio M. Vignola, Jean Bousquet
Publikováno v:
Scopus-Elsevier
Patients with glucocorticoid (GC)-dependent asthma present an ongoing inflammation of the airways despite chronic long-term treatment with oral GC. Interleukin (IL)-8 and granulocyte/macrophage colony-stimulating factor (GM-CSF) have been implicated
Autor:
Rosalia Gagliardo, Philippe Godard, Béatrice Térouanne, Patrice Vic, Elena Altieri, Giuseppina Chiappara, Jean Bousquet, Antonio M. Vignola, Pascal Chanez, Isabelle Vachier
Publikováno v:
Scopus-Elsevier
The expression of the glucocorticoid receptor (GR) in untreated or in steroid-dependent asthmatic patients is poorly understood. We therefore studied GR mRNA and protein levels in bronchial biopsies obtained from seven untreated asthmatic patients, s
Autor:
Michel Aubier, Marina Pretolani, Pascal Chanez, Gabriel Thabut, Marie-Pierre Debray, Camille Taille, Dominique Knap, Fatima Hamidi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:1208-1209