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Autor:
Jon A. Hotchkiss, Patty Spencer, Jack R. Harkema, Kate Slack, Hye-Youn Cho, Karen Regan, Roger Hilaski
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 18:91-99
Ozone (O3) is the principal oxidant pollutant in photochemical smog. Repeated exposures to O3 induces inflammation and mucous cell metaplasia in the nasal airways of laboratory animals. Our study was designed to determine the efficacy of a topical an
Autor:
O Naess, Gordon J. Christensen, Ole Henning Skjønsberg, Theis Tønnessen, Torstein Lyberg, Finn Finsnes
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 155:1404-1412
Endothelin (ET) has strong bronchoconstrictor properties, stimulate mucus secretion and mucosal edema, and may also exert proinflammatory effects. Therefore, ET may play a pathogenic role in inflammatory airway diseases such as bronchial asthma. The
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 155:1428-1435
We examined the effect of salmeterol, a long-acting beta2-adrenergic receptor agonist, on ovalbumin-induced plasma leakage and leukocyte adhesion in tracheal blood vessels of unanesthetized brown Norway rats. Ovalbumin challenge of sensitized rats re