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Effects of Systemic and Local Immunization on Alveolar Epithelial Permeability to Protein in the Rat
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 157:324-327
This study aimed to characterize the effect on alveolar epithelial permeability to protein as a result of immunization when animals were reexposed to antigen. Antigen (bovine serum albumin [BSA]) and a related bystander protein (human serum albumin [
Autor:
Frank F. Sun, Karen P. Kolbasa, William E. Fleming, Robert L. Griffin, Jia En Chin, Bruce M. Taylor, Stephen F. Fidler, Ivan M. Richards
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 17:757-766
Increased microvascular permeability and mucosal edema are pathological features of airway inflammation in asthma. In this study, we investigated the characteristics of the edema response occurring in a model of antigen-induced lung inflammation in s
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 155:1428-1435
We examined the effect of salmeterol, a long-acting beta2-adrenergic receptor agonist, on ovalbumin-induced plasma leakage and leukocyte adhesion in tracheal blood vessels of unanesthetized brown Norway rats. Ovalbumin challenge of sensitized rats re
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 152:1796-1804
Tachykinins released from sensory airway nerves have been shown to increase vascular permeability and plasma-protein extravasation (PPE) in rodent airways. We previously demonstrated that in Fisher (F344) rats, tachykinins cause bronchoconstriction m