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Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 152:1796-1804
Tachykinins released from sensory airway nerves have been shown to increase vascular permeability and plasma-protein extravasation (PPE) in rodent airways. We previously demonstrated that in Fisher (F344) rats, tachykinins cause bronchoconstriction m
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 151:1165-1169
The possible role of nitric oxide (NO) in the regulation of airway tone remains to be fully explored. In the present study we examined the effect of NG-nitro-L-arginine methyl ester (L-NAME), an inhibitor of NO synthase, on airway responsiveness in r
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 6:307-314
Pulmonary surfactant is critical for gas exchange and is composed of both phospholipids and specific surfactant-associated proteins. The most abundant surfactant protein is termed surfactant apoprotein A (SP-A). This protein is thought to be importan