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Autor:
Emmanuelle Born, Jean-Michel Flaman, Charles Fouillade, Roger Le Grand, Larissa Lipskaia, Serge Adnot, Quentin Pascal, Arturo London-Vallejo, David Bernard, Pauline Maisonnasse, Valentin Sencio, François Trottein
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2021, ⟨10.1165/rcmb.2021-0205le⟩
American Journal of Respiratory Cell and Molecular Biology, 2021, ⟨10.1165/rcmb.2021-0205le⟩
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, In press, ⟨10.1165/rcmb.2021-0205LE⟩
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2021, ⟨10.1165/rcmb.2021-0205le⟩
American Journal of Respiratory Cell and Molecular Biology, 2021, ⟨10.1165/rcmb.2021-0205le⟩
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, In press, ⟨10.1165/rcmb.2021-0205LE⟩
International audience
Autor:
Stuti Agarwal, Aradhana Mohan, Balaji Krishnamachary, Priscilla Y. Hsue, Ling Chen, Ashok Kumar, Navneet K. Dhillon, Alison Morris, Prabhakar Chalise, Aatish Mahajan
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Am J Respir Cell Mol Biol
Am J Respir Cell Mol Biol
Extracellular vesicles (EVs) have emerged as important mediators in cell–cell communication; however, their relevance in pulmonary hypertension (PH) secondary to human immunodeficiency virus (HIV) infection is yet to be explored. Considering that c
Publikováno v:
Am J Respir Cell Mol Biol
The extracellular matrix (ECM), a highly organized network of structural and nonstructural proteins, plays a pivotal role in cellular and tissue homeostasis. Changes in the ECM are critical for normal tissue repair, whereas dysregulation contributes
Autor:
Cécile Macquin, Philippe Georgel, Hamid Merdji, Mohamad Kassem, Seiamak Bahram, Kei Kurihara, Aurore De Cauwer, Alicia Sibony, Julie Helms, Chérine Abou Fayçal, Raphaël Clere-Jehl, Laetitia Minniti, Ferhat Meziani
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Septic shock and disseminated intravascular coagulation (DIC) are known to be characterized by an endothelial cell dysfunction. The molecular mechanisms underlying this relationship are, however, poorly understood. In this work, we aimed to investiga
Autor:
Uday Kishore, Ekta Gupta, Hrishikesh Pandit, Indra Kundu, Sheetalnath Rooge, Savneet Kaur, Reshu Agarwal, Sanjeev Gupta, Taruna Madan, Dinesh M. Tripathi, Susan Idicula-Thomas, Praveen M. Varghese, Rambhadur Subedi, Barnali Biswas
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
RationaleCOVID-19 is an acute infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Human surfactant protein D (SP-D) is known to interact with spike protein of SARS-CoV, but its immune-surveillance against SA
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Coronavirus disease (COVID-19), the clinical syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently a global health pandemic with substantial morbidity and mortality. COVID-19 has cast a shadow on nearly every a
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Pulmonary fibrosis is a progressive and fatal lung disease characterized by activation of lung fibroblasts and excessive deposition of collagen matrix. We show here that the concentrations of kindlin-2 and its binding partner PYCR1, a key enzyme for
Autor:
Michael Novotny, Ian C. Davis, Lucia E. Rosas, Lisa M Joseph, R. Duncan Hite, Hasan El-Musa, Judy M. Hickman-Davis, Lauren M. Doolittle
Publikováno v:
Am J Respir Cell Mol Biol
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology
There is an urgent need for new drugs for patients with acute respiratory distress syndrome (ARDS), including those with coronavirus disease (COVID-19). ARDS in influenza-infected mice is associated with reduced concentrations of liponucleotides (ess
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic. In addition to the acute pulmonary symptoms of coronavirus disease (COVID-19) (the disease associated with SARS-CoV-2 infection), pulmonary and distal
Autor:
Ji Min Li, Wen Hsin Chang, Ssu-Wei Hsu, Shenwen Gu, David C. Yang, Ching-Hsien Chen, Szu Jung Chen
Publikováno v:
Am J Respir Cell Mol Biol
Tobacco smoking is a well-known risk factor for both fibrogenesis and fibrotic progression; however, the mechanisms behind these processes remain enigmatic. RTKs (receptor tyrosine kinases) have recently been reported to drive profibrotic phenotypes