Zobrazeno 1 - 10
of 17
pro vyhledávání: ''
Autor:
Sergio Harari, Olga Torre, Wendy K. Steagall, Joel Moss, Thomas N. Darling, Gustavo Pacheco-Rodriguez
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:678-683
Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, affecting lungs, kidneys, and lymphatics. It is caused by the proliferation of abnormal smooth muscle–like LAM cells, with mutations and loss of heterozygosity in the TSC1 or, more f
Publikováno v:
S382
S374
S374
The mitochondrion is the main site of energy production and a hub of key signaling pathways. It is also central in stress-adaptive response due to its dynamic morphology and ability to interact with other organelles. In response to stress, mitochondr
Autor:
Soo In Kim, Hyun Ah Song, Min Jung Kang, Hyun Jin Min, Ji Hyun Kim, Yoo Suk Kim, Hyung Ju Cho, Joo Heon Yoon, Ju Wan Kang, Chang Hoon Kim
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Hypoxia resulting from occlusion of the sinus ostium is known to be one of the major pathogenic mechanisms of sinusitis. Hypoxia-inducible factor (HIF)-1 is a widely known transcription factor that induces the cellular response to hypoxic conditions
Autor:
Manfred Frick, Boris Mizaikoff, Paul Dietl, Kristin E. Thompson, Christiane Michel, Peter Braubach, Hanna Schmidt, Michael Fauler, Oliver H. Wittekindt, Daniel Neubauer
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:372-382
The apical surface liquid (ASL) layer covers the airways and forms a first line of defense against pathogens. Maintenance of ASL volume by airway epithelia is essential for maintaining lung function. The proteolytic activation of epithelial Na+ chann
Autor:
Weiqun He, Xiaoqing Liu, Pu Mao, Yimin Li, Songlin Wu, Xiaoqing Pang, Yongbo Huang, Haibo Zhang, Arthur S. Slutsky, Jianchun Li
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:11-19
Lung epithelial-mesenchymal transition (EMT) plays an important role in ventilation-associated lung fibrosis, which may contribute to the poor outcome of patients with acute respiratory distress syndrome. Because microRNAs control and modulate normal
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:633-644
Idiopathic pulmonary fibrosis is a chronic and progressive lung disease in which microvessel remodeling is deregulated. However, the mechanism by which deregulated angiogenesis contributes to the pathogenesis of pulmonary fibrosis remains unclear. He
Autor:
Mohan K. Raizada, Gilberto O Lobaton, Aline C. Oliveira, Ravindra K. Sharma, Jeffrey K. Harrison, Victor Aquino, Elaine M. Richards, Andrew Bryant
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 59:271-273
Publikováno v:
Am J Respir Cell Mol Biol
Research to understand the contribution of macrophages to nonresolving airway inflammation in cystic fibrosis (CF) and other chronic suppurative airways diseases has been hindered by a lack of methods for isolating and studying these cells. With the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63dc524a7ff846b5505397430051844
https://europepmc.org/articles/PMC6604218/
https://europepmc.org/articles/PMC6604218/
Autor:
Robert M. Tighe, John W. Hollingsworth, Paul W. Noble, Yen-Rei A. Yu, Andrew J. Ghio, Danielle F. Hotten, Yuryi Malakhau, Michael D. Gunn, Monica Kraft, Ellen Volker
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:13-24
Clear identification of specific cell populations by flow cytometry is important to understand functional roles. A well-defined flow cytometry panel for myeloid cells in human bronchoalveolar lavage (BAL) and lung tissue is currently lacking. The obj
Autor:
Patricia A. Thistlethwaite
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 57:15-17