Zobrazeno 81 - 90
of 186
pro vyhledávání: ''
Autor:
Barbara Bacci, Kenneth J. Snibson, Chrishan S. Samuel, Peter Bradding, Cameron J. Nowell, Wayne G. Kimpton, Katy M. Roach, Emmanuel Koumoundouros, Jade Jaffar, Louise Organ, Glen P. Westall
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:539-550
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease of increasing prevalence marked by poor prognosis and limited treatment options. Ca2+-activated KCa3.1 potassium channels have been shown to play a key role in the aberrant activat
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 195:912-920
Combination lumacaftor/ivacaftor has been shown to improve lung function and other endpoints in patients aged 12 years and older with cystic fibrosis and homozygous for F508del-CFTR, but it has not been assessed in younger patients.In this open-label
Autor:
Daniel Dorgan, Richard J. Wallace, Barbara A. Brown-Elliott, Keith Liu, Gina Eagle, Patrick A. Flume, Kevin L. Winthrop, Charles L. Daley, Kenneth N. Olivier, Doreen Addrizzo-Harris, David E. Griffith, John P. McGinnis, Stephen J. Ruoss, Renu Gupta, Matthias Salathe, Liza Micioni
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 195:814-823
Lengthy, multidrug, toxic, and low-efficacy regimens limit management of pulmonary nontuberculous mycobacterial disease.In this phase II study, we investigated the efficacy and safety of liposomal amikacin for inhalation (LAI) in treatment-refractory
Autor:
Sebastian Ochoa, Fayez Kheir, Sumit Chatterji, Sebastian Fernandez-Bussy, Adnan Majid, George Cheng, Erik Folch, Estefania Rivera
Publikováno v:
Annals of the American Thoracic Society. 14:342-346
Exudative pleural effusions may arise secondary to inflammation of intra-abdominal structures. Pleural space loculations can complicate these effusions, preventing adequate chest tube drainage and leading to consideration of surgical intervention. Pr
Autor:
de Montmollin, Etienne, Demeret, Sophie, Brule, Noëlle, Conrad, Marie, Dailler, Frédéric, Lerolle, Nicolas, Navellou, Jean-Christophe, Schwebel, Carole, Alves, Mikael, Cour, Martin, Engrand, Nicolas, Tonnelier, Jean-Marie, Maury, Eric, Ruckly, Stephane, Picard, Géraldine, Rogemond, Véronique, Magalhaes, Éric, Sharshar, Tarek, Timsit, Jean-François, Honnorat, Jérome, Sonneville, Romain, Study Group, ENCEPHALITICA, Louart, Benjamin
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2017, 195 (4), pp.491-499. ⟨10.1164/rccm.201603-0507OC⟩
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2017, 195 (4), pp.491-499. ⟨10.1164/rccm.201603-0507OC⟩
International audience; RATIONALE:Encephalitis caused by anti-N-methyl-d-aspartate receptor (NMDAR) antibodies is the leading cause of immune-mediated encephalitis. There are limited data on intensive care unit (ICU) management of these patients.OBJE
Autor:
James C. Watson, Louise A. Durst, Gabriel L. Pagani-Estévez, Keith M. Swetz, Susan K. Tointon, Michael D. McGoon, Robert P. Frantz, Ann M. Karnyski
Publikováno v:
Annals of the American Thoracic Society. 14:206-212
Prostacyclin-associated leg pain is a potentially debilitating adverse effect of prostacyclin therapy for patients with pulmonary arterial hypertension (PAH). However, to our knowledge, this entity has not been systematically studied.To characterize
Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial
Autor:
Harold I. Palevsky, Corey E. Ventetuolo, James R. Klinger, Kathleen J. Propert, Frank Z. Stanczyk, Anjali Vaidya, Mary Whittenhall, Amy Palmisciano, M. Patel, Diane Pinder, Bonnie Ky, Russell P. Tracy, K. Akaya Smith, Angela DeMichele, Jason S. Fritz, Steven M. Kawut, Christine Archer-Chicko
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 195:360-368
Rationale: The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy in treating patients with pulmonary arterial hypertension (PAH) is unknown.Objectives: We aim
Autor:
Yoshihiko Hoshino, Masahiro Shimojima, Atsuyuki Kurashima, Naoki Hasegawa, Shunsuke Shibuya, Kiyohiko Izumi, Kozo Morimoto, Takashi Yoshiyama, Satoshi Mitarai, Jun Sokunaga, Manabu Ato, Ho Namkoong, Kazuhiro Uchimura
Publikováno v:
Annals of the American Thoracic Society. 14:49-56
Since 2010, mycobacterial examination results have been used widely to survey nontuberculous mycobacteria (NTM) lung disease.To reveal the clinical and epidemiological status of NTM lung disease in Japan.All data on the isolation and identification o
Autor:
David B. Kantor, Joel N. Hirschhorn, Nicole Stenquist, Craig D Smallwood, Molly C McDonald, Kyle A. Nelson, Blake J. Schultz, Wanda Phipatanakul
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 194:1552-1555
Autor:
Garry R. Cutting, Joseph M. Collaco, Karen S. Raraigh, Michael R. Knowles, Johanna M. Rommens, Patrick R. Sosnay, Pierre-Yves Boëlle, Lisa J. Strug, Rhonda G. Pace, John McGready, Scott M. Blackman, Harriet Corvol
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 194:1375-1382
Expanding the use of cystic fibrosis transmembrane conductance regulator (CFTR) potentiators and correctors for the treatment of cystic fibrosis (CF) requires precise and accurate biomarkers. Sweat chloride concentration provides an in vivo assessmen