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Autor:
Cécile Macquin, Philippe Georgel, Hamid Merdji, Mohamad Kassem, Seiamak Bahram, Kei Kurihara, Aurore De Cauwer, Alicia Sibony, Julie Helms, Chérine Abou Fayçal, Raphaël Clere-Jehl, Laetitia Minniti, Ferhat Meziani
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Septic shock and disseminated intravascular coagulation (DIC) are known to be characterized by an endothelial cell dysfunction. The molecular mechanisms underlying this relationship are, however, poorly understood. In this work, we aimed to investiga
Autor:
Uday Kishore, Ekta Gupta, Hrishikesh Pandit, Indra Kundu, Sheetalnath Rooge, Savneet Kaur, Reshu Agarwal, Sanjeev Gupta, Taruna Madan, Dinesh M. Tripathi, Susan Idicula-Thomas, Praveen M. Varghese, Rambhadur Subedi, Barnali Biswas
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
RationaleCOVID-19 is an acute infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Human surfactant protein D (SP-D) is known to interact with spike protein of SARS-CoV, but its immune-surveillance against SA
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic. In addition to the acute pulmonary symptoms of coronavirus disease (COVID-19) (the disease associated with SARS-CoV-2 infection), pulmonary and distal
Autor:
Matthew N. Alder, Amy Opoka, Lin Fei, Al-Faraaz Kassam, Nick C. Levinsky, Patrick Lahni, Hector R. Wong, Jaya P Mallela, Rashmi D Sahay, Kira Angel, Vanessa Nomellini
Publikováno v:
Am J Respir Cell Mol Biol
Neutrophils are vital to both the inflammatory cascade and tissue repair after an injury. Neutrophil heterogeneity is well established but there is less evidence for significant, different functional roles for neutrophil subsets. OLFM4 (Olfactomedin-
Autor:
Ilona Jaspers, Meghan E. Rebuli, Adam M. Speen, Terry L. Noah, Jessica R. Hoffman, Parker F. Duffney, Carole Robinette, Radhika Dhingra, Ellen E. Glista-Baker, Erica A. Pawlak
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Inhalation of tobacco smoke has been linked to increased risk of viral infection, such as influenza. Inhalation of electronic-cigarette (e-cigarette) aerosol has also recently been linked to immune suppression within the respiratory tract, specifical
Autor:
E. Kaitlynn Allen, Gabriela Maron, Li Tang, Timothy Brahm, Tim Flerlage, Joshua Wolf, Jeremy Chase Crawford, Aisha Souquette, Paul G. Thomas, Brandon M. Triplett, Yilun Sun
Publikováno v:
Am J Respir Cell Mol Biol
Allogeneic hematopoietic cell-transplant (alloHCT) recipients are at increased risk of complications from viral respiratory-tract infections (vRTIs). We measured cytokine concentrations in nasal washes (NWs) from pediatric alloHCT recipients to bette
Autor:
Richard Saffery, Matthew Burton, Shivanthan Shanthikumar, Sarath Ranganathan, Melanie R Neeland
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 63:152-159
Childhood pulmonary diseases not only cause childhood morbidity and mortality but also can cause long-term pulmonary impairment. The clinical management of many childhood pulmonary diseases is hampered by a limited understanding of the underlying pat
Autor:
Belinda L. Sun, Sara M. Camp, Heather Lynn, Ankit A. Desai, Xiaoguang Sun, Haiyang Tang, Rebecca Vanderpool, Franz Rischard, Jason X.-J. Yuan, Aleksandra Babicheva, Nancy Casanova, Liliana Moreno-Vinasco, Jian Wang, Geetanjali Gupta, Carrie L. Kempf, Mohamed Ahmed, Joe G.N. Garcia, Saad Sammani, Radu C. Oita, Akash Gupta
Publikováno v:
Am J Respir Cell Mol Biol
We previously demonstrated involvement of NAMPT (nicotinamide phosphoribosyltransferase) in pulmonary arterial hypertension (PAH) and now examine NAMPT regulation and extracellular NAMPT’s (eNAMPT’s) role in PAH vascular remodeling. NAMPT transcr
Publikováno v:
Am J Respir Cell Mol Biol
Type II alveolar epithelial cells (AEC2s) play an essential role in the function and maintenance of the pulmonary epithelium. Several transgenic mice have been developed to study the function of these cells in vivo by using the human SFTPC promoter t
Autor:
Richard J. Martin, Ramadan B Sopi, Benjamin Gaston, Feifei Cui, Craig A. Hodges, Gail H. Deutsch, Rongli Zhang, Maureen O'Reilly, Anjum Jafri, Thomas M. Raffay, Peter M. MacFarlane, Laura Smith, Koby Bonilla-Fernandez
Publikováno v:
Am J Respir Cell Mol Biol
Bronchopulmonary dysplasia (BPD) is characterized by alveolar simplification, airway hyperreactivity, and pulmonary hypertension. In our BPD model, we have investigated the metabolism of the bronchodilator and pulmonary vasodilator GSNO (S-nitrosoglu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18764a262c40236cb83fe2f096719b5
https://europepmc.org/articles/PMC8320118/
https://europepmc.org/articles/PMC8320118/