Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Glenn Dranoff"'
Autor:
Robert J. Soiffer, Edwin P. Alyea, Matthias Piesche, Vincent T. Ho, Glenn Dranoff, Haesook T. Kim, Heather Daley, John Koreth, Natalie Bavli, Martin C. Mihm, Olga Pozdnyakova, Carol Reynolds, Joseph H. Antin, Jerome Ritz, Corey Cutler, Nicholas C. Souders
We report a clinical trial testing vaccination of autologous myeloblasts admixed with granulocyte-macrophage colony-stimulating factor secreting K562 cells after allogeneic hematopoietic stem cell transplantation (HSCT). Patients with myelodysplastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bbd711508bc1f6338c05e90278a60d
https://europepmc.org/articles/PMC5737123/
https://europepmc.org/articles/PMC5737123/
Publikováno v:
Blood
Studying human antigen-specific memory B cells has been challenging because of low frequencies in peripheral blood, slow proliferation, and lack of antibody secretion. Therefore, most studies have relied on conversion of memory B cells into antibody-
Autor:
Thomas Enzler, Michael Dougan, Glenn Dranoff, Darryl A. Oble, Donna Neuberg, Silke Gillessen, Martin C. Mihm, James P. Allison
Publikováno v:
Blood. 110:954-961
The pathogenesis of type 1 diabetes (T1D) involves the immune-mediated destruction of insulin-producing β cells in the pancreatic islets of Langerhans. Genetic analysis of families with a high incidence of T1D and nonobese diabetic (NOD) mice, a pro
Autor:
Glenn Dranoff, Silke Gillessen, Richard A. Van Etten, Michael H. Tomasson, Shaoguang Li, D. Gary Gilliland
Publikováno v:
Blood. 97:1442-1450
Primitive hematopoietic progenitors from some patients with Philadelphia chromosome (Ph)–positive chronic myeloid leukemia (CML) express aberrant transcripts for interleukin 3 (IL-3) and granulocyte colony-stimulating factor (G-CSF), and exhibit au
Autor:
Jerome Ritz, Sarah Snykers, Sarah Nikiforow, Nikhil C. Munshi, Heather Daley, Matthew Jacobs, Helene Negre, Rachel Allen, Joana M. Murad, Heidi Dipietro, Robert J. Soiffer, Donna Neuberg, Charles L. Sentman, Glenn Dranoff, Randie E White, Frederic Lehmann, Lillian Werner, Robert L. Schlossman, Ilene Galinsky, Susanne H.C. Baumeister, Richard Stone, Adam Schmucker, Lauren Johnston, Sarah Patches, Jake Reder, Terri K. Wade, Kristen Cummings
Publikováno v:
Blood. 128:4052-4052
Introduction: Conventional CAR-T cells express a single chain antibody variable fragment that restricts recognition to one tumor antigen and a limited set of cancers. This study employs a novel CAR fusing full-length human NKG2D with the CD3z signali
Autor:
Kimura S, Timothy Gainsford, Robb L, Richard C. Mulligan, Andrew W. Roberts, Warren S. Alexander, D Metcalf, Begley Cg, Glenn Dranoff
Publikováno v:
Blood. 91:2745-2752
Mice lacking thrombopoietin (TPO), or its receptor c-Mpl, display defective megakaryocyte and platelet development and deficiencies in progenitor cells of multiple hematopoietic lineages. The contribution of alternative cytokines to thrombopoiesis in
Publikováno v:
Blood. 99:2603-2605
Erythropoietin (EPO) and its receptor (EPOR) are critical for definitive erythropoiesis, as mice lacking either gene product die during embryogenesis with severe anemia. Here we demonstrate that mice expressing just one functional allele of the EpoR
Autor:
Philippe Morel, Glenn Dranoff, Shohreh Zarei, P. Luy, Frank Schwenter, Manfred Kopf, Nicolas Mach, Michel Aurrand-Lions
Publikováno v:
Blood, Vol. 113, No 26 (2009) pp. 6658-6668
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a potent adjuvant in cancer vaccination; however, the specific role of endogenous GM-CSF remains unknown. We performed cell-based vaccination in 2 tumor models. First, we vaccinated C57BL/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171af9b3d49017570c14369e70f55486
https://europepmc.org/articles/PMC2943756/
https://europepmc.org/articles/PMC2943756/
Autor:
Robert J. Soiffer, Jerome Ritz, Daniel J. DeAngelo, Donna Neuberg, Vincent T. Ho, Richard Stone, Matthew Vanneman, Masahisa Jinushi, Glenn Dranoff, Catia Fonseca
The identification of cancer antigens that contribute to transformation and are linked with immune-mediated tumor destruction is an important goal for immunotherapy. Toward this end, we screened a murine renal cell carcinoma cDNA expression library w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5197f1f122160b0143746bc6f443133d
https://europepmc.org/articles/PMC2647666/
https://europepmc.org/articles/PMC2647666/
Autor:
Joseph H. Antin, Di Wu, Philippe Armand, Jerome Ritz, Natalie R. Goldstein, Mildred Pasek, Corey Cutler, Kristen E. Stevenson, Donna Neuberg, Robert J. Soiffer, Tetsuro Sasada, Vincent T. Ho, Christine Canning, Jennifer R. Brown, Glenn Dranoff, John Koreth, Ute E. Burkhardt, Edwin P. Alyea, Ursula Hainz, Catherine J. Wu
Publikováno v:
Blood. 120:1892-1892
Abstract 1892 Patients with advanced hematological malignancies remain at high risk for eventual disease progression following reduced intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (allo-HSCT). We hypothesized that v