Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Daniel B. Bellissimo"'
Autor:
Maria M. Brooks, Eric H. Kraut, Margaret V. Ragni, Craig D. Seaman, Leslie J. Raffini, Annette von Drygalski, Daniel B. Bellissimo, Rajiv K. Pruthi, Jonathan C. Roberts, Peter A. Kouides
Publikováno v:
Blood. 138:1044-1044
Introduction It is well established that von Willebrand factor (VWF) levels increase with age among healthy adults. Recently, there is emerging research demonstrating this may also occur in patients with von Willebrand disease (VWD), particularly typ
Autor:
Amy L. Dunn, Adam Cuker, David Green, Cindy A. Leissinger, J. Gill, Abraham C. Schlauderaff, Bryce A. Kerlin, D. M. Di Michele, Joan Cox Gill, F. Shafer, A. Shapiro, Steven R. Lentz, Deborah L Brown, Madhvi Rajpurkar, Janna M. Journeycake, Robert R. Montgomery, Veronica H. Flood, Sandra L. Haberichter, Michael J. Paidas, Carolyn M. Bennett, Michael D. Tarantino, Roshni Kulkarni, Carol Diamond, Kenneth D. Friedman, Liesl Mathias, A. Matsunaga, Anne T. Neff, Paula M. Jacobi, Thomas C. Abshire, A. Bedros, Daniel B. Bellissimo, Margaret V. Ragni, M L Manco-Johnson, Tricia L. Slobodianuk, Pamela A. Christopherson, Barbara A. Konkle, Anjali Sharathkumar, Peter A. Kouides, A. Cohen, Eric J. Werner, John J. Strouse, Ralph A. Gruppo, Dagmar T. Stein, Jeffrey D. Hord, Raymond G. Hoffmann, Lisa N. Boggio, Leonard A. Valentino, Jeanne M. Lusher, Alice D. Ma, Donald H. Mahoney, Patricia J. Giardina
Publikováno v:
Blood. 125:2297-2304
Von Willebrand factor (VWF) contains binding sites for platelets and for vascular collagens to facilitate clot formation at sites of injury. Although previous work has shown that VWF can bind type IV collagen (collagen 4), little characterization of
Autor:
Michael J. Meyer, Margaret M. Leech, Sriya Gunawardena, Franklin A. Bontempo, Daniel B. Bellissimo, John Uhrmacher
Publikováno v:
Blood. 132:5053-5053
A 15-year-old African-American male with a history of thrombosis was examined for the Factor V HR2 sequence variation (c.3980A>G, p.H1327R) using PCR followed by RsaI digestion. An anomalous restriction pattern was observed: one strand was uncut (wil
Autor:
Robert R. Montgomery, Sandra L. Haberichter, Joan Cox Gill, Pamela A. Christopherson, Amy D. Shapiro, Margaret V. Ragni, W. Keith Hoots, Kenneth D. Friedman, Thomas C. Abshire, Cindy A. Leissinger, Jeanne M. Lusher, Veronica H. Flood, Daniel B. Bellissimo
Publikováno v:
Blood. 119:2135-2140
Diagnosis and classification of VWD is aided by molecular analysis of the VWF gene. Because VWF polymorphisms have not been fully characterized, we performed VWF laboratory testing and gene sequencing of 184 healthy controls with a negative bleeding
Autor:
Stefana Gavazova, Michael Balistreri, Patricia A. Morateck, Joan Cox Gill, Marilyn J. Manco-Johnson, Sandra L. Haberichter, Daniel B. Bellissimo, Robert R. Montgomery, Pamela A. Christopherson
Publikováno v:
Blood. 108:3344-3351
Type 1 von Willebrand disease (VWD) is characterized by a partial quantitative deficiency of von Willebrand factor (VWF). Few VWF gene mutations have been identified that cause dominant type 1 VWD. The decreased survival of VWF in plasma has recently
Autor:
Robert R. Montgomery, Rupa A Udani, Pamela A. Christopherson, Sandra L. Haberichter, Veronica H. Flood, C. L. Perry, Kenneth D. Friedman, Joan Cox Gill, Zimmerman Program Investigators, Daniel B. Bellissimo
Publikováno v:
Blood. 128:872-872
von Willebrand Disease (VWD) is a common inherited bleeding disorder caused by a quantitative or qualitative abnormality of von Willebrand Factor (VWF). Genetic analysis for VWD commonly utilizes DNA sequencing to identify sequence variants (SV) in V
Autor:
Kenneth D. Friedman, Sandra L. Haberichter, Daniel B. Bellissimo, Rupa A Udani, Robert R. Montgomery, Pamela A. Christopherson, Joan Cox Gill, Veronica H. Flood
Publikováno v:
Blood. 126:758-758
Type 1 von Willebrand disease (VWD) is a common inherited bleeding disorder, characterized by a quantitative deficiency of von Willebrand factor (VWF). The molecular basis continues to merit exploration, especially since the genetic cause has not bee
Autor:
Veronica H. Flood, Robert R. Montgomery, Pamela A. Christopherson, Rupa A Udani, Daniel B. Bellissimo, Joan Cox Gill, Kenneth D. Friedman, Sandra L. Haberichter
Publikováno v:
Blood. 124:2833-2833
[Graphic][1] Von Willebrand disease (VWD) is caused by quantitative (types 1 and 3) and qualitative (type 2) defects in von Willebrand factor (VWF). VWD type 1 and 2 are autosomal dominant with variable expression while type 3 is autosomal recessive.
Publikováno v:
Blood. 124:563-563
Sickle cell disease (SCD) is an inherited autosomal recessive blood disorder associated with significant morbidity. Nonmyeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used in severely affected patients with SCD
Autor:
Pamela A. Christopherson, Ian R. Peake, Crystal L. Perry, Daniel J. Hampshire, Daniel B. Bellissimo, Anne Goodeve, Robert R. Montgomery, Ashley Cartwright, Sandra L. Haberichter
Publikováno v:
Blood. 124:1525-1525
Introduction: In recent years, the role of copy number variation (CNV) in the pathogenesis of type 1 von Willebrand disease (VWD) has been extensively explored. Large cohort studies including the MCMDM-1VWD and French studies have identified a total