Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christina M. Annunziata"'
Autor:
Christina M. Annunziata, Laurence Lamy, Lidia Hernandez, Adriana Zingone, Elaine M. Hurt, W. Michael Kuehl, Arthur L. Shaffer, Louis M. Staudt, Lloyd T. Lam, R. Eric Davis
Publikováno v:
Blood. 117:2396-2404
Modulating aberrant transcription of oncogenes is a relatively unexplored opportunity in cancer therapeutics. In approximately 10% of multiple myelomas, the initiating oncogenic event is translocation of musculoaponeurotic fibrosarcoma oncogene homol
Publikováno v:
Blood. 96:2841-2848
The malignant Reed-Sternberg cell of Hodgkin disease is an aberrant B cell that persists in an immunolgically mediated inflammatory infiltrate. Despite its nonproductive immunoglobulin genes, the Reed-Sternberg cell avoids the usual apoptotic fate of
Autor:
Kenneth C. Carter, Craig A. Rosen, Steven C. Barash, Paola Ricciardi-Castagnoli, Louis M. Staudt, Patrick J. Dillon, Christina M. Annunziata, Jeffrey Cossman, Wei-Wu He
Publikováno v:
Blood. 94:411-416
The malignant Reed-Sternberg cell of Hodgkin’s disease, first described a century ago, has resisted in-depth analysis due to its extreme rarity in lymphomatous tissue. To directly study its genome-wide gene expression, approximately 11,000,000 base
Autor:
Christina M. Annunziata, Arik Cooper, Constantinos Petrovas, David R. Ambrozak, Sara Ferrando-Martinez, David Kotlyar, Richard A. Koup, Takuya Yamamoto, Joseph P. Casazza, Lidia Hernandez
Publikováno v:
Blood. 124:4142-4142
Background: Reactivation of HIV from latently infected T cells with oncologic agents (such as vorinostat) has been proposed as a means to potentially reduce or eliminate the HIV reservoir. A CDK9 inhibitor used in hematologic malignancies, flavopirid
Autor:
Irina Maric, Christina M. Annunziata, Neha Korde, Mark Raffeld, Mary Ann Yancey, Beata Holkova, Maciej Kmieciak, Steven Grant, Daniel C. Sullivan, Jin-Qiu Chen, Ola Landgren, Katherine R. Calvo, Marcia Mulquin, Adriana Zingone, Liqiang Xi, Austin Doyle
Publikováno v:
Blood. 118:306-306
Abstract 306 Gene expression profiling previously defined 7 molecularly distinct multiple myeloma (MM) subgroups associated with clinical behavior. The MMSET/FGFR3 subgroup, harboring the t(4;14) translocation, and the MAF subgroup including t(14;16)