Zobrazeno 1 - 10
of 26
pro vyhledávání: '"A. Malvar"'
Autor:
Todd M. Cooper, Xiaojing Yang, Yoav Messinger, Alan S. Wayne, Andrew E. Place, Richard Sposto, Jemily Malvar, Bodour Salhia, Weili Sun, Luciano Dalla-Pozza, Lia Gore, Henrique Bittencourt, Gangning Liang, Chris Fraser, Paul S. Gaynon, Timothy J. Triche, Peter A. Jones
Publikováno v:
Blood. 131:1145-1148
TO THE EDITOR: Despite improvements in treating childhood leukemia, relapses remain the primary cause of death.[1][1][⇓][2][⇓][3]-[4][4] On relapse, leukemic cells are more resistant to chemotherapy. Thus, there is an urgent need to incorporate n
Autor:
Andrew Doan, Holly K.T. Huang, Ari J. Hadar, Jemily Malvar, Teresa Rushing, Gordana Raca, Alexandra E. Kovach, Paul Gaynon, Etan Orgel
Publikováno v:
Blood. 138:2342-2342
Children with acute myeloid leukemia (AML) are commonly treated using a daunorubicin-cytarabine ±etoposide (DA/ADE) backbone as developed by the Medical Research Council (MRC) AML 12 trial and since adopted by the Children's Oncology Group (COG). Th
Autor:
Nirali N. Shah, Eric S Schafer, Kenneth Matthew Heym, Andrew E. Place, Melissa A. Burns, Nathan Gossai, Peter Shaw, Michael J. Burke, Bill H. Chang, Michelle L. Hermiston, Reuven J Schore, Teresa Rushing, Paul F Jarosinski, Richard Sposto, Ellynore Florendo, Jemily Malvar, Yueh-Yun Chi, James A. Whitlock, Lewis B. Silverman, Deepa Bhojwani, Alan S. Wayne
Publikováno v:
Blood. 138:3402-3402
Introduction: Vincristine intensification has the potential to improve outcomes in ALL, but severe neurotoxicity has prohibited escalation beyond standard capped doses. Vincristine sulfate liposome injection, VSLI (Marqibo®) is a liposomal formulati
Publikováno v:
Blood. 138:4234-4234
Introduction Emicizumab is a recombinant, humanized bispecific monoclonal antibody that mimics the function of factor VIII (FVIII) which results in a significant reduction in the annualized bleeding rate in patients with hemophilia A (HA), however, t
Publikováno v:
Blood
Background: COVID-19 in adults with cancer results in substantial rates of severe infection (>25%) and death (13%) that are more than two-fold those in adults without cancer. Data from a few cohorts of COVID-19 in children with cancer, most of whom h
Autor:
Jemily Malvar, Amy Stillings, Lingyun Ji, Neil A. Goldenberg, Nihal Bakeer, Arash Mahajerin, Richard Sposto, Julie Jaffray, John H. Fargo, Luis M. Ahumada, E Vince S Faustino, Emily Krava, Hannah Lonsdale, Michael Silvey, Neil A. Zakai, Ali Jalali, Guy Young, James D. Cooper, Brian R. Branchford, Stacy E. Croteau
Publikováno v:
Blood. 134:635-635
Introduction Incidence of pediatric hospital-acquired venous thromboembolism (HA-VTE) is increasing raising concern for acute and chronic sequelae and impact on the health care system. This has prompted many pediatric centers to implement prophylaxis
Publikováno v:
Blood. 134:1134-1134
Introduction: Patients with severe factor VIII (FVIII) deficiency are defined as having a FVIII level of Methods Patients with mild/moderate hemophilia (group 1) and severe FVIII deficient patients with inhibitors and on steady-state emicizumab (grou
Autor:
Sarah H. O'Brien, Janice M. Staber, Robert F. Sidonio, Angela C. Weyand, Julie Jaffray, Peter A. Kouides, Jemily Malvar, Amy Stillings, Kristina M. Haley
Publikováno v:
Blood. 134:628-628
Introduction Because of an increased awareness by the medical community of von Willebrand Disease (VWD) in females with heavy menstrual bleeding (HMB), diagnostic laboratory testing is often sent by primary care clinicians and obstetricians/gynecolog
Autor:
Mark C. Walters, Christopher C. Dvorak, Michael A. Pulsipher, Nancy Bunin, May Al Jassani, Sonali Chaudhury, Mitchell S. Cairo, Carrie L. Kitko, Allison P. Jacob, Eric Anderson, Julie-An Talano, Dimitri S. Monos, Jemily Malvar, Leung Wing, Hisham Abdel-Azim
Publikováno v:
Blood. 134:4624-4624
MRD detected by flow cytometry (FC) or PCR has been associated with key outcomes after HCT for ALL. In a prospective multicenter trial (NCT02646839; Pediatric Blood and Marrow Transplant Consortium [PBMTC] ONC1401), we performed a planned sub-study o
Autor:
Waseem Alhushki, Jonathan Tucci, Jemily Malvar, Hisham Abdel-Azim, Etan Orgel, Richard Sposto, David R. Freyer, Steven D. Mittelman, Cecilia Fu
Publikováno v:
Blood. 124:3932-3938
Obesity is associated with poorer event-free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). Persistent minimal residual disease (MRD) in the bone marrow as measured by multidimensional flow cytometry (MDF) is a key early prognostic i