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pro vyhledávání: '"Xiaoyan Wang"'
Autor:
Zulema Romero, Edward J. Rebar, Andrew Wilber, Roger P. Hollis, Matthew C. Mendel, Lei Zhang, Fabrizia Urbinati, David Gray, Alok V. Joglekar, Michael L. Kaufman, Allen Zhu, Shantha Senadheera, Michael C. Holmes, Aaron R. Cooper, Philip D. Gregory, David Paschon, Michelle Ho, Megan D. Hoban, Dianne Lumaquin, Donald B. Kohn, Gregory J. Cost, Andreas Reik, Georgia R. Lill, Xiaoyan Wang, Pei-Qi Liu
Publikováno v:
Blood. 125:2597-2604
Sickle cell disease (SCD) is characterized by a single point mutation in the seventh codon of the β-globin gene. Site-specific correction of the sickle mutation in hematopoietic stem cells would allow for permanent production of normal red blood cel