Zobrazeno 241 - 250
of 2 018
pro vyhledávání: '"11"'
Publikováno v:
Blood. 120:4952-4952
Abstract 4952 Introduction: MDS are a heterogeneous group of hematologic disorders associated with clonal evolution of abnormal erythroid, myeloid and megakaryocytic lineages. Risk of transformation to acute myeloid leukemia (AML) is determined by IP
Autor:
Katsuji Kaida, Ruri Kato, Toshihiro Soma, Yoshihiro Fujimori, Satoshi Yoshihara, Shinichi Ishii, Masaya Okada, Kazuhiro Ikegame, Takayuki Inoue, Hiroyasu Ogawa, Hiroya Tamaki
Publikováno v:
Blood. 120:4203-4203
Abstract 4203 The major drawback of HLA-haploidentical stem cell transplantation is graft-versus-host disease (GVHD): however, the GVHD can be overcome using substantial T cell depletion method (Perugia), the use of a high dose ATG (Beijing), or the
Autor:
Kristen P. Hook, Mark J. Osborn, Jakub Tolar, John E. Wagner, John A. McGrath, Douglas R. Keene, Bruce R. Blazar, Maria K. Hordinsky
Publikováno v:
Blood. 120:965-965
Abstract 965 It is becoming clear that bone marrow (BM) and umbilical cord blood (UCB) cells can engraft in extramedullary tissues after hematopoietic cell transplantation (HCT). On the basis of preclinical testing in an animal model of recessive dys
Autor:
Irith Baumann, Shinsuke Hirabayashi, Ayami Yoshimi-Noellke, Peter Noellke, Sandra Urbaniak, Wilfried Truckenmüller, Alexandra Fischer, Ingrid Furlan, Brigitte Schlegelberger, Marcin W. Wlodarski, Brigitte Strahm, Charlotte M. Niemeyer
Publikováno v:
Blood. 120:644-644
Abstract 644 Refractory cytopenia of the childhood (RCC) and severe aplastic anemia (SAA) are the most common causes of acquired hypoplastic bone marrow failure (BMF) in children. Although predisposing genetic factors and inciting immunological event
Autor:
Zhe Wang, Rong Liang, Xian qing Bai, Ying Guo, Luhua Wang, Guo qing Yan, Qun xie Chen, Tao Zhang, Lan Yang
Publikováno v:
Blood. 120:5105-5105
Abstract 5105 Objective: To improve the understanding of natural killer (NK)/T cell lymphoma (NK/TCL) with poor prognosis and provide experiential references via a restrospective analysis of the clinical and pathological features. Methods: 117 NK/TCL
Autor:
Sangeeta Atwal, Yogesh Jethava, Antonio Pagliuca, Hugues de Lavallade, Victor Noriega, Michelle Kenyon, Ghulam J. Mufti, Victoria T Potter, Donal P. McLornan, Kavita Raj, Anjum Bashir Khan
Publikováno v:
Blood. 120:4216-4216
Abstract 4216 Patients who relapse after allogeneic bone marrow transplant (BMT) for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) have a poor prognosis. Salvage treatments rely on further chemotherapy, donor lymphocyte infusions (
Autor:
William J. Hogan, Aref Al-Kali, Mark R. Litzow, Alexandra P. Wolanskyj, Michelle A. Elliott, Lindsey E. Roeker
Publikováno v:
Blood. 120:3555-3555
Abstract 3555 Background: Although treatment-related acute myeloid leukemia (tr-AML) has been identified as an independent marker of poor prognosis, it is important to determine how characteristics of the patient, primary malignancy, or treatment reg
Autor:
Yue Wei, Martin Nguyen, Zhihong Fang, Guillermo Garcia-Manero, Michael Fernandez, Simrit Parmar, Sherry Pierce, Hagop M. Kantarjian, Jorge E. Cortes, Carlos E. Bueso-Ramos, Qi-Rong Geng, Hui Yang
Publikováno v:
Blood. 120:3810-3810
Abstract 3810 The pathogenesis of MDS is multifactorial including both cell intrinsic alterations, such as mutations, and cell extrinsic stimuli such as inflammatory signals and immune deregulation. It has been postulated that hypomethylating agents
Autor:
Walter Fiedler, Hans Klose, Carsten Bokemeyer, Hans Jörg Baumann, Gabi Vohwinkel, Nicole Lüneburg, Jasmin Wellbrock, Jan K. Hennigs, Björn Schulz
Publikováno v:
Blood. 120:5189-5189
Abstract 5189 Background: Pulmonary arterial hypertension (PAH) is a severe and life-threatening disease. It is characterized by excessive growth of pulmonary artery endothelial and smooth muscle cells leading to a profound pulmonary artery remodelin
Publikováno v:
Blood. 120:625-625
Abstract 625 Introduction: There is little objective information about intra-articular bleeding patterns in progressive hemophilic arthropathy. When hemophiliacs present with joint pain or suspected tissue bleeding, clinical decisions are routinely b