Zobrazeno 1 - 10
of 17
pro vyhledávání: ''
Autor:
Niki Stavroyianni, Helga D. Munch-Petersen, Kenichi Yoshida, Markus Schneider, Andreas Rosenwald, German Ott, Lucile Couronné, Michael Hummel, Marita Ziepert, Daniel Noerenberg, Emma Young, Richard Rosenquist, Seishi Ogawa, Thorsten Zenz, Jonathan C. Strefford, Larry Mansouri, Rose-Marie Amini, Hans G. Drexler, Viktor Ljungström, Martin-Leo Hansmann, Mareike Frick, Dido Lenze, Martin Erlanson, Ralf Küppers, Alfredo Rivas-Delgado, Armando López-Guillermo, Elisabeth Ralfkiaer, Christopher Maximilian Arends, Magnus Hultdin, Tatjana Pandzic, Bernd Dörken, Claudia D. Baldus, Maria K. Angelopoulou, Theodora Papadaki, Kirsten Grønbæk, Kostas Stamatopoulos, Anna Tasidou, Maysaa Abdulla, Nils Waldhueter, Frederik Damm, Theodoros P. Vassilakopoulos, Elias Campo, Damien Roos-Weil, Jude Fitzgibbon, Elena Mylonas, Blanca Gonzalez, Penelope Korkolopoulou, George Kanellis, Aron Skaftason, Gunilla Enblad, Olivier A. Bernard, Fazila Asmar, Jessica Okosun, Clemens A. Schmitt, Christian Bastard
Publikováno v:
Blood. 128:2666-2670
We recently reported a truncating deletion in the NFKBIE gene, which encodes IκBε, a negative feedback regulator of NF-κB, in clinically aggressive chronic lymphocytic leukemia (CLL). Because preliminary data indicate enrichment of NFKBIE aberrati
Autor:
Alina Nicolae, Stephen M. Ansell, Sarah L. Ondrejka, Jonathan W. Said, Shridevi Karikehalli, Karen L. Grogg, Ahmet Dogan, Edgardo R. Parrilla Castellar, Wyndham H. Wilson, Andrew L. Feldman, Rhett P. Ketterling, Elaine S. Jaffe, William R. Macon, Sarah E. Gibson, Eric D. Hsi, Jagmohan S. Sidhu, Mark E. Law, Steven H. Swerdlow, Liuyan Jiang, James R. Cerhan, Cristine Allmer, Matthew J. Maurer, Kay M. Ristow, Ryan A. Knudson, George Vasmatzis, Thomas M. Habermann
Publikováno v:
Blood. 124:1473-1480
Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a CD30-positive T-cell non-Hodgkin lymphoma that morphologically resembles ALK-positive ALCL but lacks chromosomal rearrangements of the ALK gene. The genetic and clin
Autor:
Mitchell S. Cairo, James C. Lynch, Jan Delabie, Andreas Rosenwald, Yanyan Liu, Yulei Shen, Kai Fu, German Ott, Timothy C. Greiner, Karen E Deffenbacher, Cynthia M. Lachel, Dennis D. Weisenburger, Sherrie L. Perkins, Elaine S. Jaffe, Javeed Iqbal, Louis M. Staudt, Lisa M. Rimsza, Randy D. Gascoyne, Elias Campo, Megan S. Lim, Lynette M. Smith, Wing C. Chan, Zhongfeng Liu, Warren G. Sanger, Thomas G. Gross
Publikováno v:
Blood. 119:3757-3766
Burkitt lymphoma (BL) predominates in pediatric patients, whereas diffuse large B-cell lymphoma (DLBCL) is uncommon. In contrast to adults, BL and DLBCL are treated similarly in children and both entities have superior outcomes in children compared w
Autor:
Lorena Barclay, Adele Telenius, Merrill Boyle, Christian Steidl, Randy D. Gascoyne, Pedro Farinha, Douglas E. Horsman, Sohrab P. Shah, Joseph M. Connors
Publikováno v:
Blood. 116:418-427
In classical Hodgkin lymphoma (cHL) the mechanisms underlying primary refractory disease and relapse remain unknown. To gain further insight into cHL pathogenesis and genomic changes linked to treatment response, we studied 53 cHL patients by array c
Autor:
Shigeo Nakamura, Hitoshi Kiyoi, Masafumi Ito, Takumi Sugimoto, Junji Hiraga, Akihiro Tomita, Kazuyuki Shimada, Tomoki Naoe, Tomohiro Kinoshita
Publikováno v:
Blood. 113:4885-4893
Although rituximab is a key molecular targeting drug for CD20-positive B-cell lymphomas, resistance to rituximab has recently been recognized as a considerable problem. Here, we report that a CD20-negative phenotypic change after chemotherapies with
Autor:
Elaine S. Jaffe, Lisa M. Rimsza, Timothy C. Greiner, George E. Wright, Laura Wake, Chao Wang, Sharathkumar Bhagavathi, Andreas Rosenwald, Wing C. Chan, Yanyan Liu, Dennis D. Weisenburger, Yulei Shen, Kai Fu, Jan Delabie, Shuangping Guo, Joseph Rohr, Lynette M. Smith, Timothy W. McKeithan, Xin Huang, German Ott, Julie M. Vose, Javeed Iqbal, James R. Cook, Cynthia M. Lachel, Elias Campo, Randy D. Gascoyne, James O. Armitage, Rita M. Braziel, Karen E Deffenbacher, Raymond R. Tubbs, Louis M. Staudt, Karen Dybkær, Cuiling Liu
Publikováno v:
Iqbal, J, Shen, Y, Huang, X, Liu, Y, Wake, L, Liu, C, Deffenbacher, K, Lachel, C M, Wang, C, Rohr, J, Guo, S, Smith, L M, Wright, G, Bhagavathi, S, Dybkær, K, Fu, K, Greiner, T C, Vose, J M, Jaffe, E, Rimsza, L, Rosenwald, A, Ott, G, Delabie, J, Campo, E, Braziel, R M, Cook, J R, Tubbs, R R, Armitage, J O, Weisenburger, D D, Staudt, L M, Gascoyne, R D, McKeithan, T W & Chan, W C 2015, ' Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggresive B-cell lymphoma ', Blood, vol. 125, no. 7, pp. 1137-1145 . https://doi.org/10.1182/blood-2014-04-566778
We studied the global microRNA (miRNA) expression in diffuse large B-cell lymphoma (DLBCL; n = 79), Burkitt lymphoma (BL; n = 36), primary mediastinal B-cell lymphoma (PMBL; n = 12), B-cell lines (n = 11), and normal subsets of naive B cells, centrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1165355578f222bea5cb7646f741660b
https://europepmc.org/articles/PMC4326773/
https://europepmc.org/articles/PMC4326773/
Autor:
Yeon Hee Park, Jong Gwang Kim, Sang Kyun Sohn, Dong Hwan Kim, Min Kyoung Kim, Je-Jung Lee, Ho Jin Shin, Hee Du Jung, Young Rok Do, Deok-Hwan Yang, Myung Soo Hyun
Publikováno v:
Blood. 108:2720-2725
The precise mechanism of rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone (R-CHOP) therapy in diffuse large B-cell lymphoma (DLBCL) is not fully elucidated. Besides overcoming bcl-2-mediated chemoresistance, antibody-dependent cellu
Autor:
Marco Paulli, Teresa Marafioti, Georges Delsol, Laura Pasqualucci, Antonino Carbone, Michaela Cerri, Daniela Capello, Enrico Tiacci, Verena Distler, Arcangelo Liso, Gianluca Gaidano, Elias Campo, Brunangelo Falini, Stefano Pileri
Publikováno v:
Blood. 108:1013-1020
Aberrant somatic hypermutation (SHM) has been identified as a mechanism for genomewide instability in diffuse large B-cell lymphoma (DLBCL). To assess whether aberrant SHM plays a role in the molecular pathogenesis of Hodgkin lymphoma (HL), we invest
Autor:
José García-Laraña, Vicens Romagosa, Abel Sánchez-Aguilera, Juan F. García, Carmen Bellas, Mónica García-Cosío, Concepción Nicolás, Maria J Mestre, Lydia Sanchez-Verde, Miguel A. Piris, Alberto Fernández de Sevilla, Manuel M. Morente, Carlos Montalbán, Manuel F. Fresno, Pilar Sabin, Javier Menárguez, Mariano Provencio, Miguel Méndez, Paloma de la Cueva
Publikováno v:
Blood. 108:662-668
Around 20% to 30% of patients with Hodgkin lymphoma (HL) do not benefit from standard therapies and finally succumb to their disease. The factors that influence the outcome of HL have not been elucidated, underscoring the demand for the identificatio
Autor:
Stefano Monti, Nancy L. Harris, Christine Ladd, Françoise Berger, Thomas M. Habermann, Todd R. Golub, Wen Jing, Margaret A. Shipp, Jon C. Aster, Jeffery L. Kutok, Gilles Salles, Riccardo Dalla-Favera, Paola Dal Cin, Ricardo C.T. Aguiar, Paul J. Kurtin, Laurence de Leval, Friedrich Feuerhake, Donna Neuberg, Geraldine S. Pinkus, Giorgio Cattoretti, Sigui Li, Kerry J. Savage
Publikováno v:
Blood. 102:3871-3879
Mediastinal large B-cell lymphoma (MLBCL) is a recently identified subtype of diffuse large B-cell lymphoma (DLBCL) that characteristically presents as localized tumors in young female patients. Although MLBCL has distinctive pathologic features, it