Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stanford J, Stewart"'
Autor:
Charles L, Vogel, Melody A, Cobleigh, Debu, Tripathy, John C, Gutheil, Lyndsay N, Harris, Louis, Fehrenbacher, Dennis J, Slamon, Maureen, Murphy, William F, Novotny, Michael, Burchmore, Steven, Shak, Stanford J, Stewart, Michael, Press
Publikováno v:
Journal of Clinical Oncology. 41:1638-1645
PURPOSE To evaluate the efficacy and safety of first-line, single-agent trastuzumab in women with HER2-overexpressing metastatic breast cancer. PATIENTS AND METHODS One hundred fourteen women with HER2-overexpressing metastatic breast cancer were ran
Autor:
Dennis J. Slamon, Mansoor N. Saleh, Stanford J. Stewart, Joanne E. Mortimer, Andrew Arnold, Debasish Tripathy, Melody A. Cobleigh, M. Murphy
Publikováno v:
Journal of Clinical Oncology. 22:1063-1070
Purpose In a pivotal phase III trial, the addition of trastuzumab to chemotherapy significantly improved response rate, time to disease progression, and overall survival in women with HER2 overexpressing metastatic breast cancer. We conducted an exte
Autor:
John K. Erban, Kathy D. Miller, Mark D. Pegram, Denise A. Yardley, Elizabeth Tan-Chiu, Seila Liv, Stanford J. Stewart, Hope S. Rugo
Publikováno v:
Journal of Clinical Oncology. 32:TPS671-TPS671
TPS671^ Background: Response to trastuzumab (T)-based chemoimmunotherapy in metastatic breast cancer segregates according to expression of the Fcg receptor, CD16A, allotypes with patients homozygou...
Autor:
Howard A. Burris, Todd M. Bauer, Giuseppe Giaccone, Jan Baughman, Seock-Ah Im, Hua Li, Stanford J. Stewart, Jane B. Trepel, David A Carlin, Jeffrey L. Nordstrom, Yung-Jue Bang
Publikováno v:
Journal of Clinical Oncology. 31:3004-3004
3004 Background: The anti-HER2 MAb, trastuzumab (H), has proven effective for HER2+ breast cancer (BC) and gastroesophageal cancer (GEC). H’s mechanism of action is incompletely understood, but evidence indicates ADCC is important. MGAH22 is an Fc-