Zobrazeno 1 - 10
of 74
pro vyhledávání: '"BUZDAR, A"'
Autor:
Filip Janku, Ecaterina Ileana Dumbrava, Vivek Subbiah, Aung Naing, Shubham Pant, Daniel D. Karp, Funda Meric-Bernstam, David S. Hong, Aman U. Buzdar, Ishwaria Mohan Subbiah, Apostolia Maria Tsimberidou, Jordi Rodon, Siqing Fu, Timothy A. Yap
Publikováno v:
Journal of Clinical Oncology. 38:12044-12044
12044 Background: While safety and dose-finding remain the primary objective of Phase 1 trials, the potential for clinical benefit has taken a greater meaning in the last decade with the novel therapies. With data from phase I trials being submitted
Autor:
Mitch Dowsett, Alistair Ring, Ivana Sestak, Aman U. Buzdar, Michael Baum, Anthony Howell, John F. Forbes, Jack Cuzick
Publikováno v:
Journal of Clinical Oncology. 29:4266-4272
Purpose The Arimidex, Tamoxifen Alone or in Combination (ATAC) study was a double-blind randomized trial in which postmenopausal women with early-stage breast cancer were assigned to receive anastrozole, tamoxifen, or the combination. We have conduct
Autor:
Emma Quinn, Anthony Howell, Janine Salter, John F. Forbes, Andrew R. Green, Mitch Dowsett, Silvia Pineda, Jack Cuzick, Elizabeth Mallon, Lila Zabaglo, Ian O. Ellis, C. Wale, Aman U. Buzdar
Publikováno v:
Journal of Clinical Oncology. 29:4273-4278
Purpose We recently reported that the mRNA-based, 21-gene Genomic Health recurrence score (GHI-RS) provided additional prognostic information regarding distant recurrence beyond that obtained from classical clinicopathologic factors (age, nodal statu
Autor:
Charles Coombes, Francesco Boccardo, Judith M Bliss, Jim Ingle, John F. Forbes, Jon Godwin, Richard Peto, Jack Cuzick, Alan S. Coates, Claire Snowdon, Michael J. Baum, Raimund Jakesz, C Davies, Mitch Dowsett, Marco Colleoni, Marc Buyse, Michael Gnant, Aman U. Buzdar, Manfred Kaufmann
Publikováno v:
Journal of Clinical Oncology. 28:509-518
Purpose To conduct meta-analyses of randomized trials of aromatase inhibitors (AIs) compared with tamoxifen either as initial monotherapy (cohort 1) or after 2 to 3 years of tamoxifen (cohort 2). Materials and Methods Data submitted to the Early Brea
Autor:
Craig Allred, H Bishop, Jill Knox, Pauline J Carder, Denis Larsimont, F Knox, Mitch Dowsett, Ian O. Ellis, Joan Houghton, Janine Salter, Chris Wale, Hironobu Sasano, Antonio Llombart Cussac, Norman R. Williams, Valerie Speirs, Jack Cuzick, Emma Quinn, John F. Forbes, Elizabeth Mallon, Aman U. Buzdar
Publikováno v:
Journal of Clinical Oncology. 26:1059-1065
Purpose To determine the relationship between quantitative estrogen-receptor (ER) and progesterone-receptor (PgR) expression and human epidermal growth factor 2 (HER-2) status with time to recurrence (TTR) in postmenopausal women with hormone recepto
Autor:
Henry L. Gomez, Daniel J. Booser, Vicente Valero, Keith Anderson, Lajos Pusztai, Richard L. Theriault, Peter J. Dempsey, Aman U. Buzdar, Roman Rouzier, Nuhad K. Ibrahim, Gabriel N. Hortobagyi, Tatiana Vidaurre, Jeffrey S. Ross, Nour Sneige, Kenneth R. Hess, Jaime A. Mejia, W. Fraser Symmans
Publikováno v:
Journal of Clinical Oncology. 24:4236-4244
Purpose We developed a multigene predictor of pathologic complete response (pCR) to preoperative weekly paclitaxel and fluorouracil-doxorubicin-cyclophosphamide (T/FAC) chemotherapy and assessed its predictive accuracy on independent cases. Patients
Autor:
Aman U. Buzdar, Sean E. McGuire, Thomas A. Buchholz, Massimo Cristofanilli, Roman Rouzier, Henry Mark Kuerer, Paolo Morandi, Ana M. Gonzalez-Angulo, Vicente Valero, Gabriel N. Hortobagyi, Susan L. Tucker, Alberto Ocaña, Shu Wan Kau, Eugene H. Huang
Publikováno v:
Journal of Clinical Oncology. 23:7098-7104
Purpose To identify clinicopathological factors predictive of distant metastasis in patients who had a pathologic complete response (pCR) after neoadjuvant chemotherapy (NC). Methods Retrospective review of 226 patients at our institution identified
Autor:
Thomas A. Buchholz, Henry Mark Kuerer, Aman U. Buzdar, Naomi R. Schechter, Kelly K. Hunt, Eugene H. Huang, Vicente Valero, Aysegul A. Sahin, George H. Perkins, Gabriel N. Hortobagyi, Eric A. Strom, Marsha D. McNeese, Susan L. Tucker
Publikováno v:
Journal of Clinical Oncology. 22:4691-4699
Purpose To evaluate the efficacy of radiation in patients treated with neoadjuvant chemotherapy and mastectomy. Patients and Methods We retrospectively analyzed the outcomes of 542 patients treated on six consecutive institutional prospective trials
Autor:
Daniel J. Booser, Stephen E. Jones, Eric P. Winer, Allen S. Melemed, Aman U. Buzdar, Patrick Peterson, John E. Pippen, Joyce A. O'Shaughnessy, Clifford A. Hudis, Pamela N. Munster
Publikováno v:
Journal of Clinical Oncology. 21:1007-1014
Purpose: To select a daily dose of arzoxifene ( LY353381 ), a selective estrogen receptor modulator, for use in future studies in women with locally advanced or metastatic breast cancer who are either potentially tamoxifen sensitive (TS) or tamoxifen
Autor:
CK Osborne, C. Morris, M. Ellis, J.T. May, J. Pippen, A. Buzdar, S.E. Jones, Gary V. Burton, A. Webster, Steven E. Come, Richard M. Elledge, Stan Gertler, I. Dimery, Leroy M. Parker
Publikováno v:
Journal of Clinical Oncology. 20:3386-3395
PURPOSE: To compare the efficacy and tolerability of fulvestrant (formerly ICI 182,780) with anastrozole in the treatment of advanced breast cancer in patients whose disease progresses on prior endocrine treatment. PATIENTS AND METHODS: In this doubl