Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Melody A. Cobleigh"'
Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Autor:
David M. Loesch, Nicholas J. Robert, Robert N. Raju, Robert M. Sayre, Dennis J. Slamon, Kathy S. Albain, Elizabeth Valentine, Brian Leyland-Jones, Lea Fuchs, Cecelia McCullough, Lina Asmar, R. J. Belt, Melody A. Cobleigh, Des Ilegbodu
Publikováno v:
Journal of Clinical Oncology. 24:2786-2792
Purpose This randomized, multicenter, phase III trial evaluated the efficacy and safety of trastuzumab and paclitaxel with or without carboplatin as first-line therapy for women with HER-2–overexpressing metastatic breast cancer (MBC). Patients and