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pro vyhledávání: '"Yung-Ming Chen"'
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:978-986
Monocyte/macrophage infiltration to the subendothelial space of arterial wall is a critical initial step in atherogenesis, in which CC chemokine ligand 2 (CCL2)/monocyte chemoattractant protein-1 (MCP-1) is thought to play a key role. This study inve
Autor:
Tun-Jun Tsai, Shuei-Liong Lin, Ruey-Hwa Chen, Yung-Ming Chen, Bor-Shen Hsieh, Wen-Chih Chiang
Publikováno v:
Molecular Pharmacology. 64:811-822
Pentoxifylline (PTX) is a potent inhibitor of mesangial cell proliferation, but its underlying mechanism is poorly understood. Here, we demonstrate that in platelet-derived growth factor (PDGF)-stimulated mesangial cells, PTX causes G1 arrest by down