Zobrazeno 1 - 2
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pro vyhledávání: '"Chen Liang"'
Autor:
Xi Zhang, Chen-liang Guo, Jia-li Liu, Guo-Rui Gao, Xiang Wang, Jian Ding, Sufen Cao, Linghua Meng, Wenhu Duan, Linjiang Tong
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 348:432-441
Phosphatidylinositol 3-kinase, α isoform (PI3Kα) plays essential roles in cell metabolism, growth, and proliferation and has been validated as a promising anticancer target. In an effort to search for new PI3Kα-selective inhibitors, DW series comp
Publikováno v:
Molecular Pharmacology. 63:1322-1328
Nitric oxide (NO) is known to affect synaptic plasticity in various regions of the brain via the cGMP-cGMP-dependent protein kinase (PKG) pathway. We found that a novel compound 3-(5-hydroxymethyl-2-furyl)-1-benzyl-indazole (YC-1), a drug known to mo