Zobrazeno 1 - 10
of 22
pro vyhledávání: '"López-Arencibia A"'
Autor:
Angélica Domínguez-De Barros, Atteneri López-Arencibia, Nuria E. Campillo, José E. Piñero, Ines Sifaoui, Jacob Lorenzo-Morales, María Reyes-Batlle, Víctor Sebastián-Pérez, Carmen Gil
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Antimicrob Agents Chemother
instname
Antimicrob Agents Chemother
36 p.-6 fig.-4 tab.
Pathogenic and opportunistic free-living amoebae such as Acanthamoeba spp. can cause keratitis (Acanthamoeba keratitis [AK]), which may ultimately lead to permanent visual impairment or blindness. Acanthamoeba can also cause
Pathogenic and opportunistic free-living amoebae such as Acanthamoeba spp. can cause keratitis (Acanthamoeba keratitis [AK]), which may ultimately lead to permanent visual impairment or blindness. Acanthamoeba can also cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ed69cc8020e45cc3174a85567db70f
http://hdl.handle.net/10261/229004
http://hdl.handle.net/10261/229004
Autor:
Jacob Lorenzo-Morales, Morena L. Martínez, Atteneri López-Arencibia, Marvin J. Núñez, Ignacio A. Jiménez, Carlos J. Bethencourt-Estrella, Isabel L. Bazzocchi, José E. Piñero, Desirée San Nicolás-Hernández
Publikováno v:
Antimicrob Agents Chemother
Leishmaniasis and Chagas are among the most significant neglected tropical diseases. Due to several drawbacks with the current chemotherapy, developing new antikinetoplastid drugs has become an urgent issue. In the present work, a bioassay-guided inv
Autor:
María Reyes-Batlle, Ines Sifaoui, Jacob Lorenzo-Morales, Ángel Gutiérrez-Ravelo, Atteneri López-Arencibia, José E. Piñero, Daniel García-Velázquez, Carmen M. Martín-Navarro
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:2867-2874
The in vitro activity of a novel group of compounds, hexaazatrinaphthylene derivatives, against two species of Leishmania is described in this study. These compounds showed a significant dose-dependent inhibition effect on the proliferation of the pa
Autor:
María Reyes-Batlle, Ines Sifaoui, José E. Piñero, Atteneri López-Arencibia, Carmen M. Martín-Navarro, Sutherland K. Maciver, Basilio Valladares, Jacob Lorenzo-Morales, Enrique Martínez-Carretero
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:2817-2824
Members of the genus Acanthamoeba are facultative pathogens of humans, causing a sight-threatening keratitis and a life-threatening encephalitis. In order to treat those infections properly, it is necessary to target the treatment not only to the tro
Autor:
Sutherland K. Maciver, Atteneri López-Arencibia, Emilie Fouque, Antonio Osuna, Ines Sifaoui, María Reyes-Batlle, Jacob Lorenzo-Morales, Carmen M. Martín-Navarro, José E. Piñero, Yann Héchard, Basilio Valladares
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (6), ⟨10.1128/AAC.02660-16⟩
Martín-Navarro, C M, López-Arencibia, A, Sifaoui, I, Reyes-Battle, M, Fouque, E, Osuna, A, Valladares, B, Piñero, J E, Héchard, Y, Maciver, S K & Lorenzo-Morales, J 2017, ' Amoebicidal activity of caffeine and maslinic acid by the induction of Programmed Cell Death in Acanthamoeba ', Antimicrobial Agents and Chemotherapy . https://doi.org/10.1128/AAC.02660-16
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 61 (6), ⟨10.1128/AAC.02660-16⟩
Martín-Navarro, C M, López-Arencibia, A, Sifaoui, I, Reyes-Battle, M, Fouque, E, Osuna, A, Valladares, B, Piñero, J E, Héchard, Y, Maciver, S K & Lorenzo-Morales, J 2017, ' Amoebicidal activity of caffeine and maslinic acid by the induction of Programmed Cell Death in Acanthamoeba ', Antimicrobial Agents and Chemotherapy . https://doi.org/10.1128/AAC.02660-16
Free-living amoebae of the genus Acanthamoeba are the causal agents of a sight-threatening ulceration of the cornea called Acanthamoeba keratitis, as well as the rare but usually fatal disease granulomatous amoebic encephalitis. Although there are ma
Autor:
Atteneri López-Arencibia, Ines Sifaoui, María Reyes-Batlle, José E. Piñero, Jacob Lorenzo-Morales, Carmen M. Martín-Navarro, Sutherland K. Maciver, Carolina Wagner
Publikováno v:
López-Arencibia, A, Martín-Navarro, C, Sifaoui, I, Reyes-Batlle, M, Wagner, C, Lorenzo-Morales, J, Maciver, S K & Piñero, J E 2017, ' Perifosine mechanisms of action in Leishmania species ', Antimicrobial Agents and Chemotherapy . https://doi.org/10.1128/AAC.02127-16
Here the mechanism by which perifosine induced cell death in Leishmania donovani and Leishmania amazonensis is described. The drug reduced Leishmania mitochondrial membrane potential and decreased cellular ATP levels while increasing phosphatidylseri
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