Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jin Meng"'
Autor:
Hassan M. Mahsoub, C. Lynn Heffron, Anna M. Hassebroek, Harini Sooryanarain, Bo Wang, Tanya LeRoith, Guillermo Raimundi Rodríguez, Debin Tian, Xiang-Jin Meng
Publikováno v:
mBio. 14
HEV causes adverse pregnancy outcomes, with a mortality rate of >30% in pregnant women, but the underlying mechanisms are poorly understood. In this study, we utilized HEV-3ra and its cognate host (pregnant rabbit) to delineate the potential underlyi
Autor:
Bo Wang, Hassan M. Mahsoub, Wen Li, C. Lynn Heffron, Debin Tian, Anna M. Hassebroek, Tanya LeRoith, Xiang-Jin Meng
HEV-3 causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. RBV is the main therapeutic option for chronic hepatitis E as an off-label use. Chronic hepatitis E virus (HEV) infection has become a significant clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8de98d6ac8f854f6dd712b69cfb4c5
https://hdl.handle.net/10919/114160
https://hdl.handle.net/10919/114160
Publikováno v:
mBio
mBio, Vol 12, Iss 3 (2021)
mBio, Vol 12, Iss 3 (2021)
Progesterone is crucial for the maintenance of pregnancy. During pregnancy hepatitis E virus (HEV) infection is associated with increased fulminant hepatic failure and mortality rates. In this study, we determined whether progesterone modulates HEV r
Publikováno v:
mBio
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03103-19 (2020)
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03103-19 (2020)
Hepatitis E virus (HEV) is an important human pathogen causing both acute and chronic viral hepatitis E infection. Currently, the mechanisms of HEV replication and pathogenesis remain poorly understood. The innate immune response acts as the first li
Autor:
Junghyun Ryu, Danielle M. Yugo, Nathaniel Jue, Sakthivel Subramaniam, Sherrie Clark-Deener, Dianjun Cao, Shannon R. Matzinger, Xiang-Jin Meng, Kyungjun Uh, Thomas E. Cecere, Kiho Lee, Christopher Overend, Lijuan Yuan, Scott P. Kenney, Tanya LeRoith, Harini Sooryanarain, C. Lynn Heffron
Publikováno v:
Journal of Virology. 92
Hepatitis E virus (HEV), the causative agent of hepatitis E, is an important but incompletely understood pathogen causing high mortality during pregnancy and leading to chronic hepatitis in immunocompromised individuals. The underlying mechanisms lea
Autor:
Anshuman Das, Asuka Hirai-Yuki, Olga González-Láópez, Bethany Rhein, Sven Moller-Tank, Rachel Brouillette, Lucinda Hensley, Ichiro Misumi, William Lovell, John M. Cullen, Jason K. Whitmire, Wendy Maury, Stanley M. Lemon, Xiang-Jin Meng
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
mBio
mBio, Vol 8, Iss 5, p e00969-17 (2017)
mBio
mBio, Vol 8, Iss 5, p e00969-17 (2017)
Receptor molecules play key roles in the cellular entry of picornaviruses, and TIM1 (HAVCR1) is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. However, its identification as the hepatoviru
Autor:
Adam J. Rogers, Xiang-Jin Meng, Yogesh A. Karpe, Mary Etna Haac, Dianjun Cao, Harini Sooryanarain
Publikováno v:
Journal of Virology. 91
Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, generally causes self-limiting acute viral hepatitis, although chronic HEV infection has recently become a significant clinical problem in immunocompromised individuals, especially
Autor:
Rita Czakó, Leatrice Vogel, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Ali H. Ellebedy, Rafi Ahmed, Andrew Mehle, Kanta Subbarao, Xiang-Jin Meng
Publikováno v:
mBio, Vol 8, Iss 3, p e00714-17 (2017)
mBio, Vol 8, Iss 3 (2017)
mBio
mBio, Vol 8, Iss 3 (2017)
mBio
Immunization is the cornerstone of seasonal influenza control and represents an important component of pandemic preparedness strategies. Using a bioluminescent reporter virus, we demonstrate the application of noninvasive in vivo imaging system (IVIS
Publikováno v:
Journal of Clinical Microbiology. 52:1045-1051
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in people in many developing countries and is also endemic in many industrialized countries. Mammalian HEV (mHEV) isolates can be divided into at least four recognized major genotypes.
Autor:
Dianjun Cao, Lei Zhou, Xiang-Jin Meng, Patrick G. Halbur, Yao-Wei Huang, Yan-Yan Ni, Tanja Opriessnig
Publikováno v:
Ni, Y-Y, Opriessnig, T, Zhou, L, Cao, D, Huang, Y-W, Halbur, P G & Meng, X-J 2013, ' Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of virus envelope genes from genetically divergent strains ', Journal of Virology, vol. 87, no. 1, pp. 304-13 . https://doi.org/10.1128/JVI.01789-12
Molecular breeding via DNA shuffling can direct the evolution of viruses with desired traits. By using a positive-strand RNA virus, porcine reproductive and respiratory syndrome virus (PRRSV), as a model, rapid attenuation of the virus was achieved i