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Publikováno v:
Infection and Immunity. 85
Botulinum neurotoxins (BoNTs) are the most toxic proteins for humans but also are common therapies for neurological diseases. BoNTs are dichain toxins, comprising an N-terminal catalytic domain (LC) disulfide bond linked to a C-terminal heavy chain (
Publikováno v:
Journal of Virology. 81:13509-13518
Type I interferons (IFNs) signal through specific receptors to mediate expression of genes, which together confer a cellular antiviral state. Overexpression of the zinc finger antiviral protein (ZAP) imparts a cellular antiviral state againstRetrovir
Autor:
Kelly L. Rogers, Tony Velkov, Mohammad Abul Kalam Azad, Roger L. Nation, Jian Li, Jesmin Akter
Identifying the pathways involved in the apoptotic cell death that is associated with polymyxin-induced nephrotoxicity is crucial for the development of strategies to ameliorate this dose-limiting side effect and for the development of novel safer po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00bd8eeee405363731b0429cdbeecb4
https://europepmc.org/articles/PMC4356794/
https://europepmc.org/articles/PMC4356794/
Publikováno v:
Infection and Immunity. 73:6974-6980
Trypanosoma cruzi , the intracellular protozoan parasite that causes Chagasic cardiomyopathy, elicits a robust hypertrophic response in isolated cardiomyocytes. Previous studies established that T. cruzi -elicited cardiomyocyte hypertrophy is mediate
Publikováno v:
Infection and Immunity. 61:3098-3102
Lymph node cells (LNC) from mice infected with Trypanosoma brucei contain macrophage-like cells that inhibit interleukin-2 receptor (IL-2R) expression (M. Sileghem, A. Darji, R. Hamers, M. Van De Winkel, and P. De Baetselier, Eur. J. Immunol. 19:829-
Publikováno v:
Scopus-Elsevier
Bacitracin is a nephrotoxic antibiotic that has recently been shown to induce contractile effects in aortas isolated from rabbits by stimulating receptors for 5-hydroxytryptamine (5-HT). The possible renovascular actions of this antibiotic were inves
Autor:
J W Albright, J F Albright
Publikováno v:
Infection and Immunity. 47:176-182
The phenomenon of natural (innate) resistance is exemplified by the solid resistance of mice to infection with the rat-specific Trypanosoma lewisi. We provide more information about the mechanism of resistance in this model system. Resistance was not
Publikováno v:
Infection and Immunity. 48:292-297
We studied the adherence of [3H]thymidine-labeled axenic Entamoeba histolytica (strain HM1-IMSS) to in vitro preparations of rat and human colonic mucosa. Studies were performed with fixed or unfixed rat colonic mucosa, unfixed rat mucosa exposed to
Publikováno v:
Antimicrobial Agents and Chemotherapy. 32:190-194
The specific binding of 3H-labeled gamma-aminobutyric acid ([3H]GABA) to synaptic plasma membranes from rat brains was inhibited by various quinolonecarboxylic acid derivatives (quinolones), and these inhibitions were concentration dependent. The bin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 27:650-651
Cephalosporins inhibited gamma-aminobutyric acid receptor binding in a concentration-dependent manner in vitro. Scatchard analysis revealed that cefazolin decreased the binding capacity but did not change the affinity of the receptor. It is suggested