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Autor:
Helio S. Sader, Cecilia G Carvalhaes, Mariana Castanheira, Rodrigo E. Mendes, Jennifer M. Streit
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Oritavancin displayed potent and stable activity (MIC 90 range of 0.06 to 0.5 mg/L) over a 10-year period (2010 to 2019) against Gram-positive pathogens that cause bloodstream infections (BSI), including methicillin-resistant Staphylococcus aureus (M
Publikováno v:
Antimicrob Agents Chemother
Pseudomonas aeruginosa is a common pathogen that is associated with multidrug-resistant (MDR) and carbapenem-resistant (CR) phenotypes; therefore, we investigated its resistance patterns and mechanisms by using data from the Antimicrobial Testing Lea
Publikováno v:
Antimicrob Agents Chemother
Multidrug-resistant (MDR) Pseudomonas aeruginosa presents a serious threat to public health due to its widespread resistance to numerous antibiotics. P. aeruginosa commonly causes nosocomial infections including urinary tract infections (UTI) which h
Autor:
Melis N. Anahtar, Juliet T Bramante, Douglas S. Kwon, Eric S. Rosenberg, Jiawu Xu, Virginia M. Pierce, Jeffrey M Paer, Lisa Desrosiers
Publikováno v:
Antimicrob Agents Chemother
Background: Enterococcus faecium is a major cause of clinical infections, often due to multidrug-resistant (MDR) strains. Whole genome sequencing (WGS) is a powerful tool to study MDR bacteria and their antimicrobial resistance (AMR) mechanisms. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eb5a9a4ae8519bc35f8f2e4e21f55a
https://europepmc.org/articles/PMC8765321/
https://europepmc.org/articles/PMC8765321/
Autor:
Harsimran Kaur, Raees A. Paul, Rajeev Soman, Dipali Chavan, Arunaloke Chakrabarti, Parijit Das, Kaustuv Sanyal, Sanjay Bhattacharya, Anup K. Ghosh, Shivaprakash M Rudramurthy, Dipti Sharma, Rajendra Prasad, Shreya Singh, Shamanth A Shankarnarayan, Nisha Kashyap
Publikováno v:
Antimicrob Agents Chemother
Objectives: Echinocandins are frontline antifungal agents in the management of invasive infections due to multi-drug resistant Candida auris. The study aimed to evaluate echinocandin resistance in C. auris isolates of multicentric origin, identify th
Autor:
Tiffany R Keepers, Suzannah M. Schmidt-Malan, Robin Patel, Alisa W Serio, Melissa J. Karau, Bobbi S. Pritt, Surya Chitra, Scott A. Cunningham, Jayawant N. Mandrekar
Publikováno v:
Antimicrobial Agents and Chemotherapy
Omadacycline, vancomycin, and rifampin, as well as rifampin combination therapies, were evaluated in an experimental rat model of methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis. All treatment groups had less MRSA recovered than sali
Autor:
Bing Zhao, Shengfen Wang, Yang Zheng, Hui Xia, Xichao Ou, Yanlin Zhao, Yuanyuan Song, Dongxin Liu, Frank Cobelens, Wencong He, Susan van den Hof, Yang Zhou
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
Microbiology Spectrum
Microbiology spectrum, 9(3):e00409-21. American Society for Microbiology
Microbiology Spectrum
Microbiology spectrum, 9(3):e00409-21. American Society for Microbiology
We designed this study to determine the trend of moxifloxacin resistance among multidrug-resistant tuberculosis (MDR-TB) patients from 2007 to 2013 in China to inform the composition of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB
Publikováno v:
J Clin Microbiol
The Clinical and Laboratory Standards Institute (CLSI) Subcommittee on Antimicrobial Susceptibility Testing (AST) develops and publishes standards and guidelines for AST methods and results interpretation in an annual update to the Performance Standa
Autor:
Felipe Francisco Tuon, Lavinia Nery Villa Stangler Arend, Larissa Bail, Kleber Oliveira Silva, Simone Sebold Michelotto, Carmen Antonia Sanches Ito, Keite da Silva Nogueira
Publikováno v:
J Clin Microbiol
We evaluated the performance of ceftazidime-avibactam and ceftolozane-tazobactam MicroScan Neg multidrug-resistant MIC 1 (NMR1) panel for clinical carbapenem-nonsusceptible Gram-negative bacilli isolates. We evaluated 212 clinically significant carba
Publikováno v:
Antimicrobial Agents and Chemotherapy
Rifamycins, such as rifampicin (Rif), are potent inhibitors of bacterial RNA polymerase (RNAP) and are widely used antibiotics. Rifamycin resistance is usually associated with mutations in RNAP that preclude rifamycin binding. However, some bacteria