Zobrazeno 1 - 10
of 503
pro vyhledávání: ''
Autor:
Changbai Huang, Fei Feng, Yongxia Shi, Wenhui Li, Ziqiao Wang, Yunkai Zhu, Shuai Yuan, Dandan Hu, Jun Dai, Qiqi Jiang, Rong Zhang, Chao Liu, Ping Zhang
Publikováno v:
Microbiology Spectrum. 10
Infection by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has posed a severe threat to global public health. The current study revealed that several inhibitors of protein kinases C (PKCs) possess protective activity against SA
Publikováno v:
J Virol
Interactions between the N-terminal (assembly) domain (NTD) and the linker region of the hepatitis B virus (HBV) capsid protein and the large (L) envelope protein are required for virion formation, which occurs via budding of cytoplasmic mature nucle
Autor:
Dewen Tong, Liyan Cao, Xin Zhang, Da Shi, Fang Fu, Jianbo Liu, Yong Huang, Li Feng, Jianfei Chen, Hongyan Shi
Publikováno v:
J Virol
Porcine parvovirus (PPV) NS1, the major nonstructural protein of this virus, plays an important role in PPV replication. We show, for the first time, that NS1 dynamically shuttles between the nucleus and cytoplasm, although its subcellular localizati
Autor:
Jun-Gyu Park, Mun-Il Kang, Mahmoud Soliman, Sang-Ik Park, Ja-Young Seo, Yeong-Bin Baek, Kyoung-Oh Cho
Publikováno v:
Journal of Virology
Group A rotavirus (RVA), one of the leading pathogens causing severe acute gastroenteritis in children and a wide variety of young animals worldwide, induces apoptosis upon infecting cells. Though RVA-induced apoptosis mediated via the dual modulatio
Autor:
Anjali Anil, Shilpa Madhavan, Akhila Parthasarathy, Anirban Banerjee, Jincy Joseph, Shruti Apte
Publikováno v:
J Bacteriol
Streptococcus pneumoniae invades a myriad of host tissues following efficient breaching of cellular barriers. However, strategies adopted by pneumococcus for evasion of host intracellular defenses governing successful transcytosis across host cellula
Autor:
Andy S. Moon, Jihui Sha, Peter J. Bradley, Allan L. Chen, Rebecca R. Pasquarelli, Jessica H Chern, James A. Wohlschlegel
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio
The cytoskeleton of Toxoplasma gondii is composed of the inner membrane complex (IMC) and an array of underlying microtubules that provide support at the periphery of the parasite. Specific subregions of the IMC carry out distinct roles in replicatio
Autor:
Zhenzhen Wang, Huijun Lu, Feng Gao, Jiyu Guan, Kui Zhao, Wenqi He, Lijun Lv, Yungang Lan, Zi Li, Yanlong Zhou, Mengshi Xu, Deguang Song, Hongbin He, Pin Lv
Publikováno v:
Journal of Virology
Orf virus (ORFV) is a highly epitheliotropic parapoxvirus with zoonotic significance that induces proliferative lesions in the skin of sheep, goats, and humans. Several viral proteins carried by ORFV, including nuclear factor-κB (NF-κB) inhibitors,
Publikováno v:
J Virol
While it is well established that microtubules (MTs) facilitate various stages of virus replication, how viruses actively control MT dynamics and functions remains less-well understood. Recent work has begun to reveal how several viruses exploit End-
Autor:
Yue Zheng, Heidi L. Schubert, Parmit K. Singh, Iván D'Orso, Christopher P. Hill, Vicente Planelles, Alan Engelman, Laura J. Martins
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
mBio
mBio
The HIV-1 latent reservoir is the major barrier to an HIV cure. Due to low levels or lack of transcriptional activity, HIV-1 latent proviruses in vivo are not easily detectable and cannot be targeted by either natural immune mechanisms or molecular t
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
mBio
mBio
Stress and virus infection regulate lipid metabolism. Human cytomegalovirus (HCMV) infection induces fatty acid (FA) elongation and increases the abundance of lipids with very-long-chain FA (VLCFA) tails. While reprogramming of metabolism can be stre