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Publikováno v:
J Virol
Interactions between the N-terminal (assembly) domain (NTD) and the linker region of the hepatitis B virus (HBV) capsid protein and the large (L) envelope protein are required for virion formation, which occurs via budding of cytoplasmic mature nucle
Autor:
Dewen Tong, Liyan Cao, Xin Zhang, Da Shi, Fang Fu, Jianbo Liu, Yong Huang, Li Feng, Jianfei Chen, Hongyan Shi
Publikováno v:
J Virol
Porcine parvovirus (PPV) NS1, the major nonstructural protein of this virus, plays an important role in PPV replication. We show, for the first time, that NS1 dynamically shuttles between the nucleus and cytoplasm, although its subcellular localizati
Autor:
Jun-Gyu Park, Mun-Il Kang, Mahmoud Soliman, Sang-Ik Park, Ja-Young Seo, Yeong-Bin Baek, Kyoung-Oh Cho
Publikováno v:
Journal of Virology
Group A rotavirus (RVA), one of the leading pathogens causing severe acute gastroenteritis in children and a wide variety of young animals worldwide, induces apoptosis upon infecting cells. Though RVA-induced apoptosis mediated via the dual modulatio
Autor:
Zhenzhen Wang, Huijun Lu, Feng Gao, Jiyu Guan, Kui Zhao, Wenqi He, Lijun Lv, Yungang Lan, Zi Li, Yanlong Zhou, Mengshi Xu, Deguang Song, Hongbin He, Pin Lv
Publikováno v:
Journal of Virology
Orf virus (ORFV) is a highly epitheliotropic parapoxvirus with zoonotic significance that induces proliferative lesions in the skin of sheep, goats, and humans. Several viral proteins carried by ORFV, including nuclear factor-κB (NF-κB) inhibitors,
Publikováno v:
J Virol
While it is well established that microtubules (MTs) facilitate various stages of virus replication, how viruses actively control MT dynamics and functions remains less-well understood. Recent work has begun to reveal how several viruses exploit End-
Autor:
Wenjiao Wu, Shuyin Gu, Shuwen Liu, Qiao Zhang, Yingyuan Zhong, Lizhu Chen, Yilu Ye, Qi Huang, Mingkai Feng
Publikováno v:
J Virol
Guanylate-binding protein 7 (GBP7) belongs to the GBP family, which plays key roles in mediating innate immune responses to intracellular pathogens. Thus far, GBP7 has been reported to be a critical cellular factor against bacterial infection. Howeve
Publikováno v:
J Virol
Autophagy is a catabolic process contributing to intrinsic cellular defense by degrading viral particles or proteins; however, several viruses hijack this pathway for their own benefit. The role of autophagy during human cytomegalovirus (HCMV) replic
Autor:
Andrew D. Yurochko, Meaghan H. Hancock, Patrizia Caposio, Hillary M. Struthers, Jay A. Nelson, Daniel N. Streblow, Lindsey B. Crawford, Felicia Goodrum
Publikováno v:
J Virol
In human cytomegalovirus (HCMV)-seropositive patients, CD34(+) hematopoietic progenitor cells (HPCs) provide an important source of latent virus that reactivates following cellular differentiation into tissue macrophages. Multiple groups have used pr
Autor:
Jason Buehler, Justin M. Reitsma, Felicia Goodrum, Sebastian Zeltzer, Scott S. Terhune, Michael Rak, Belen Molina
Human cytomegalovirus, HCMV, is a betaherpesvirus that establishes a lifelong latent infection in its host that is marked by recurrent episodes of reactivation. The molecular mechanisms by which the virus and host regulate entry into and exit from la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cfdf393d7b21efd8b5654172bd74b7
https://europepmc.org/articles/PMC7081901/
https://europepmc.org/articles/PMC7081901/
Autor:
Lisbeth Drozd Lund, Payal P.S. Balraadjsing, Yuri Souwer, Sebastian A. J. Zaat, Esther C. de Jong, Hanne Frøkiær
Publikováno v:
Infection and immunity, 88(1). American Society for Microbiology
Infect Immun
Infect Immun
Staphylococcus aureus has evolved different strategies to evade the immune response, which play an important role in its pathogenesis. The bacteria express and shed various cell wall components and toxins during different stages of growth that may af