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Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
mSphere
mSphere, vol 5, iss 6
mSphere
mSphere, vol 5, iss 6
Candida albicans is one of the most common pathogens of humans. One important virulence factor of C. albicans is its ability to form elongated hyphae that can invade host tissues and cause disseminated infections. Here, we show the effect of differen
Autor:
Nelson V. Simwela, Andrew P. Waters, Matthew Bogyo, Dana Aghabi, Barbara H. Stokes, David A. Fidock
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
The recent emergence of Plasmodium falciparum (PF) parasite resistance to the first line antimalarial drug artemisinin is of particular concern. Artemisinin resistance is primarily driven by mutations in the PF K13 protein, which enhance survival of
Autor:
Xiaohui Zheng, Sweta Roy, Tian Gao, Zafer Soultan, Shikha Nangia, Christopher Fortner, Dacheng Ren, Huan Gu, Huilin Ma
Publikováno v:
Appl Environ Microbiol
Bacteria can survive antibiotic treatment both by acquiring antibiotic resistance genes and through mechanisms of tolerance that are based on phenotypic changes and the formation of metabolically inactive cells. Here, we report an Enterococcus faecal
Autor:
Jeanette W. P. Teo, Zhehao Liu, Ka Lip Chew, Sophie Octavia, Bintou Ahmadou Ahidjo, Matilda Boey
Publikováno v:
J Clin Microbiol
Rapidly-growing-mycobacteria (RGM) may cause infections in patients with predisposing conditions or following direct inoculation via traumatic injury or surgery.…
Autor:
Josep Guarro, Adela Martin-Vicente, Loida López-Fernández, Javier Capilla, Patricia Navarro-Rodríguez
Publikováno v:
Antimicrob Agents Chemother
Mutations in ERG11 were detected by gene sequencing and amino acid alignment in 18 Candida tropicalis strains with different degrees of sensitivity to voriconazole (VRC). ERG11 expression, sterol content, and membrane permeability were also evaluated
Autor:
Xun Tao, Alaa R. M. Sayed, Jieqiang Zhou, Arnold Louie, Eunjeong Shin, Weiguo Liu, Yinzhi Lang, Carolin Werkman, Dhruvitkumar S. Sutaria, Nirav Shah, George L. Drusano, Bartolomé Moyá, Yuanyuan Jiao, Manasi Kamat, Kari B. Basso, Jürgen B. Bulitta
Publikováno v:
Antimicrob Agents Chemother
Mycobacterium abscessus causes serious infections that often require over 18 months of antibiotic combination therapy. There is no standard regimen for the treatment of M. abscessus infections, and the multitude of combinations that have been used cl
Publikováno v:
Antimicrob Agents Chemother
Autor:
Umberto D'Alessandro, Nuredin Mohammed, Haddijatou Mbye, Fatoumata Bojang, Joseph Okebe, Alfred Amambua-Ngwa, Aminata Seedy Jawara, Bekai Njie
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
Monitoring of Plasmodium falciparum sensitivity to antimalarial drugs in Africa is vital for malaria elimination. However, the commonly used ex vivo/in vitro 50% inhibitory concentration (IC50) test gives inconsistent results for several antimalarial
Autor:
Young Ki Choi, Ju Hwan Jeong, Elena A. Govorkova, Khristine Joy C. Antigua, Min-Suk Song, Yun Hee Baek, Richard J. Webby, Won-Suk Choi
Publikováno v:
J Virol
Laninamivir (LAN) is a long-acting neuraminidase (NA) inhibitor (NAI) with a similar binding profile in the influenza NA enzyme active site as those of other NAIs, oseltamivir (OS), zanamivir (ZAN), and peramivir, and may share common resistance mark
Autor:
Nicholas J. White, Mara K. N. Lawniczak, Darunee Chiwcharoen, Kathrin Witmer, Arjen M. Dondorp, Kesinee Chotivanich, Oliver J Watson, Virginia M. Howick, Jake Baum, Lucy C Okell, Richard D. Pearson, Michael J. Delves, Andrea Ruecker, Farah A. Dahalan, Boodtee Sornboon, Sasithon Pukrittayakamee, Sabrina Yahiya, Ursula Straschil
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial agents and chemotherapy, 65(1):e00898-20. American Society for Microbiology
Antimicrobial agents and chemotherapy, 65(1):e00898-20. American Society for Microbiology
Resistance to artemisinin-based combination therapy (ACT) in the Plasmodium falciparum parasite is threatening to reverse recent gains in reducing global deaths from malaria. While resistance manifests as delayed parasite clearance in patients, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222babf9a1a4a841550f7ebef07a8dea
https://doi.org/10.1128/aac.00898-20
https://doi.org/10.1128/aac.00898-20