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Autor:
Xiao-Yang Zhang, Jian-Jun Wang, Guang-Ying Li, Hong-Zhao Li, Chang-Zheng Zhang, Qian-Xing Zhuang, Kang Xi, Jing-Ning Zhu, Bin Li
Publikováno v:
Journal of Clinical Investigation. 128:5413-5427
The subthalamic nucleus (STN) is an effective therapeutic target for deep brain stimulation (DBS) for Parkinson's disease (PD), and histamine levels are elevated in the basal ganglia in PD patients. However, the effect of endogenous histaminergic mod