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Autor:
Teresa Helsten, Sharon H. Choi, Sanford J. Shattil, Mark H. Ginsberg, Thomas A. Bunch, Danny L. Brower, Alison L. Jannuzi, Hisashi Kato, Jun Yamanouchi, Chloé C. Féral
Publikováno v:
Molecular Biology of the Cell. 19:3589-3598
Integrin-mediated cell adhesion is essential for development of multicellular organisms. In worms, flies, and vertebrates, talin forms a physical link between integrin cytoplasmic domains and the actin cytoskeleton. Loss of either integrins or talin