Zobrazeno 1 - 6
of 6
pro vyhledávání: ''
Autor:
Laura G. Sánchez-Lozada, Carlos A. Roncal-Jimenez, Miguel A. Lanaspa, Christina Cicerchi, Nanxing Li, Masanari Kuwabara, Ana Andres-Hernando, Richard J. Johnson, Fernando E. García-Arroyo
Dietary, fructose-containing sugars have been strongly associated with the development of nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that fructose also can be produced via the polyol pathway in the liver, where it may induce hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ffb9b036dbba21a74b7e958d3f3032
https://europepmc.org/articles/PMC6422088/
https://europepmc.org/articles/PMC6422088/
Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the broadly used Chinese medicinal herb Stephaniae tetrandrae, exhibits potent antitumor effects and has the potential to be used as a cancer chemotherapeutic agent. We previously reported t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410380da7b7ff066635361a596a5c33b
https://europepmc.org/articles/PMC3471698/
https://europepmc.org/articles/PMC3471698/
Autor:
Tim Lahm, Mircea Ivan, Walter C. Hubbard, Alicja Bielawska, Kevin C. Wang, Lina M. Obeid, Xue Wu, Cecilia M. Devlin, Mary Van Demark, Irina Petrache
To understand the mechanisms of ceramide-based responses to hypoxia, we performed a mass spectrometry-based survey of ceramide species elicited by a wide range of hypoxic conditions (0.2-5% oxygen). We describe a rapid, time-dependent, marked up-regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bc852c10838642a72097cd5a8da2a2
https://europepmc.org/articles/PMC3366827/
https://europepmc.org/articles/PMC3366827/
The androgen receptor (AR) has a critical role in the growth and progression of androgen-dependent and castration-resistant prostate cancers. To identify novel inhibitors of AR transactivation that block growth of prostate cancer cells, a luciferase-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42f46a2606b1e3f176af2765b7d78db
https://europepmc.org/articles/PMC3390614/
https://europepmc.org/articles/PMC3390614/
Altered expression of chondroitin sulfate (CS) and heparan sulfate (HS) at the surfaces of tumor cells plays a key role in malignant transformation and tumor metastasis. Previously we demonstrated that a Lewis lung carcinoma (LLC)-derived tumor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0601d3a8bab7e41a4c73395bc2144e41
https://europepmc.org/articles/PMC3365932/
https://europepmc.org/articles/PMC3365932/
Group VIA phospholipase A(2) (iPLA(2)β) in pancreatic islet β-cells participates in glucose-stimulated insulin secretion and sarco(endo)plasmic reticulum ATPase (SERCA) inhibitor-induced apoptosis, and both are attenuated by pharmacologic or geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dc43b7b02b4ac88a261b3a189211bb
https://europepmc.org/articles/PMC3285329/
https://europepmc.org/articles/PMC3285329/