Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Valmik Bhargava"'
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
External anal sphincter (EAS), external urethral sphincters, and puborectalis muscle (PRM) have important roles in the genesis of anal and urethral closure pressures. In the present study, we defined the contribution of these muscles alone and in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f9d5e79ef29fb73c42fc0ea294c24c
https://europepmc.org/articles/PMC8742739/
https://europepmc.org/articles/PMC8742739/
Autor:
Johnny Fu, Valmik Bhargava, Ravinder K. Mittal, M. Raj Rajasekaran, My-Uyen Lilly Nguyen, Sadhana Kanoo
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 313:G581-G588
Studies show an age-related increase in the prevalence of anal incontinence and sphincter muscle atrophy. The Wnt/β-catenin signaling pathway has been recently recognized as the major molecular pathway involved in age-related skeletal muscle atrophy
Autor:
M. Raj Rajasekaran, Mitra Salehi, Youngjin Seo, Shantanu Sinha, Valmik Bhargava, Ravinder K. Mittal
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G445-G451
Obstetrical trauma to external anal sphincter (EAS) is extremely common; however, its role in the development of anal incontinence is not clear. We examined the regenerative process and functional impact of experimental surgical trauma to EAS muscle
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 306:G505-G514
The external anal sphincter (EAS) may be injured in 25–35% of women during the first and subsequent vaginal childbirths and is likely the most common cause of anal incontinence. Since its first description almost 300 years ago, the EAS was believed
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G529-G535
We recently reported that esophageal contraction reduces esophageal wall perfusion in an animal study. Our aim was to determine esophageal wall blood perfusion (EWBP) during esophageal contraction and transient lower esophageal sphincter relaxations
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G542-G547
A subthreshold pharyngeal stimulus induces lower esophageal sphincter (LES) relaxation and inhibits progression of ongoing peristaltic contraction in the esophagus. Recent studies show that longitudinal muscle contraction of the esophagus may play a
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G927-G933
Multipeaked waves (MPW) in the distal esophagus occur frequently in patients with esophageal spastic motor disorders and diabetes mellitus and are thought to represent repetitive esophageal contractions. We aimed to investigate whether the relative m
Mechanism of stretch-activated excitatory and inhibitory responses in the lower esophageal sphincter
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G397-G405
We recently found that an orally directed stretch of the esophagus activates a neurally mediated relaxation of the lower esophageal sphincter (LES). Goals of our study were to characterize the neural mechanisms responsible for axial and transverse st
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 292:G329-G334
Axial stretch: a novel mechanism of the lower esophageal sphincter relaxation. Am J Physiol Gastrointest Liver Physiol 292: G329-G334, 2007. First published October 5, 2006; doi:10.1152/ajpgi.00351.2006.-Swallow and esophageal distension-induced rela
Autor:
Nirali Patel, Melissa M. Ledgerwood, Tae Ho Kim, Valmik Bhargava, Yanfen Jiang, Ravinder K. Mittal
Esophageal axial shortening is caused by longitudinal muscle (LM) contraction, but circular muscle (CM) may also contribute to axial shortening because of its spiral morphology. The goal of our study was to show patterns of contraction of CM and LM l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1aa74455472abbfc473b5c9ed700db
https://europepmc.org/articles/PMC4556947/
https://europepmc.org/articles/PMC4556947/