Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Masaya Watanabe"'
Autor:
Takahide Kadosaka, Masaya Watanabe, Hiroyuki Natsui, Takuya Koizumi, Motoki Nakao, Taro Koya, Hikaru Hagiwara, Rui Kamada, Taro Temma, Fuyuki Karube, Fumino Fujiyama, Toshihisa Anzai
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H341-H354
SGLT2is are known to improve cardiovascular outcomes regardless of the presence of diabetes and decrease traditional cardiovascular risk factors. We demonstrated, for the first time, that EMPA inhibited PVCs by normalizing Ca2+ handling in diabetic m
Autor:
Taro Koya, Masaya Watanabe, Hiroyuki Natsui, Takahide Kadosaka, Takuya Koizumi, Motoki Nakao, Hikaru Hagiwara, Rui Kamada, Taro Temma, Toshihisa Anzai
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H869-H878
We demonstrated that pharmacological nNOS inhibition increased the atrial arrhythmia inducibility and a specific small-conductance Ca2+-activated K+ channel blocker, apamin, reversed the enhanced atrial arrhythmia inducibility. Apamin mitigated APD a
Autor:
Rui Kamada, Hisashi Yokoshiki, Masaya Watanabe, Hikaru Hagiwara, Masayuki Takahashi, Hirofumi Mitsuyama, Yumi Takahashi, Taro Temma, Toshihisa Anzai
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 320:H1456-H1469
Ventricular arrhythmia (VA) is the major cause of death in patients with left ventricular (LV) hypertrophy and/or acute ischemia. We hypothesized that apamin, a blocker of small-conductance Ca2+-activated K+ (SK) channels, alters Ca2+ handling and ex
Autor:
Takahide Kadosaka, Masaya Watanabe, Hiroyuki Natsui, Takuya Koizumi, Motoki Nakao, Taro Koya, Hikaru Hagiwara, Rui Kamada, Taro Temma, Fuyuki Karube, Fumino Fujiyama, Toshihisa Anzai
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Mar2023, Vol. 324 Issue 3, pH341-H354, 14p
Autor:
Taro Koya, Masaya Watanabe, Hiroyuki Natsui, Takahide Kadosaka, Takuya Koizumi, Motoki Nakao, Hikaru Hagiwara, Rui Kamada, Taro Temma, Toshihisa Anzai
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Nov2022, Vol. 323 Issue 5, pH869-H878, 10p
Autor:
Hisashi Yokoshiki, Masayuki Takahashi, Taro Tenma, Yutaro Otsuka, Shingo Takada, Hisataka Sabe, Masaya Watanabe, Naoya Kakutani, Rui Kamada, Hiroyuki Tsutsui, Hirofumi Mitsuyama, Kazuya Mizukami
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 315:H262-H272
The molecular and electrophysiological mechanisms of acute ischemic ventricular arrhythmias in hypertrophied hearts are not well known. We hypothesized that small-conductance Ca2+-activated K+(SK) channels are activated during hypoxia via the Ca2+/ca
Autor:
Kazuya Mizukami, Hisashi Yokoshiki, Shingo Takada, Masaya Watanabe, Taro Tenma, Hiroyuki Tsutsui, Hirofumi Mitsuyama
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H1066-H1074
Left ventricular hypertrophy is associated with an increased risk of ventricular arrhythmias. However, the underlying molecular basis is poorly understood. It has been reported that small-conductance Ca2+-activated K+ (SK) channels are involved in th
Autor:
Masayuki Takahashi, Hisashi Yokoshiki, Hirofumi Mitsuyama, Masaya Watanabe, Taro Temma, Rui Kamada, Hikaru Hagiwara, Yumi Takahashi, Toshihisa Anzai
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Apr2021, Vol. 320 Issue 4, pH1456-H1469, 14p, 2 Charts, 7 Graphs
Autor:
Taisuke Ono, Masaya Watanabe, Kazuya Mizukami, Hisashi Yokoshiki, Hiroyuki Tsutsui, Hirofumi Mitsuyama
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H86-H95
Diabetes mellitus (DM) is an independent risk of atrial fibrillation. However, its arrhythmogenic substrates remain unclear. This study sought to examine the precise propagation and the spatiotemporal dispersion of the action potential (AP) in the di
Autor:
Taro Tenma, Hirofumi Mitsuyama, Masaya Watanabe, Naoya Kakutani, Yutaro Otsuka, Kazuya Mizukami, Rui Kamada, Masayuki Takahashi, Shingo Takada, Hisataka Sabe, Hiroyuki Tsutsui, Hisashi Yokoshiki
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Aug2018, Vol. 314 Issue 8, pH262-H272, 11p