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Autor:
Kathryn J. Moore, Glenn Dranoff, Richard C. Mulligan, Vicki Rubin Kelley, Hitoshi Yokoyama, Takero Naito
Publikováno v:
American Journal of Physiology-Renal Physiology. 271:F603-F609
Conflicting reports claim that circulating interleukin (IL)-6 promotes or suppresses renal disease. Although autoimmune MRL-lpr mice have an increase in serum IL-6, and kidneys can produce IL-6, the relevance of systemic and local exposure remains un