Zobrazeno 1 - 10
of 1 068
pro vyhledávání: ''
Autor:
Danforth A. Newton, Rita M. Ryan, Manjeet K. Paintlia, Demetri D. Spyropoulos, Alan H. Jobe, Matthew W. Kemp, John E. Baatz
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Atrial natriuretic peptide (ANP) and its receptors natriuretic peptide receptor (NPR)-A and NPR-C are all highly expressed in alveolar epithelial type II cells (AEC2s) in the late-gestation ovine fetal lung and are dramatically decreased postnatally.
Publikováno v:
American Journal of Physiology-Cell Physiology. 322:C94-C110
Following anabolic stimuli (mechanical loading and/or amino acid provision), the mechanistic target of rapamycin complex 1 (mTORC1), a master regulator of protein synthesis, translocates toward the cell periphery. However, it is unknown if mTORC1-med
Autor:
Leslie E. Neidert, Matthew J. Rogatzki, L. Bruce Gladden, Brian S. Ferguson, Heidi A. Kluess, Keith R. Lohse
Publikováno v:
American Journal of Physiology-Cell Physiology. 321:C761-C769
The precise matching of blood flow to skeletal muscle during exercise remains an important area of investigation. Release of adenosine triphosphate (ATP) from red blood cells (RBCs) is postulated as a mediator of peripheral vascular tone in response
Autor:
Ghanem, Mada, Homps-Legrand, Méline, Garnier, Marc, Morer, Lise, Goletto, Tiphaine, Frija-Masson, Justine, Wicky, Paul-Henri, Jaquet, Pierre, Bancal, Catherine, Hurtado-Nedelec, Margarita, de Chaisemartin, Luc, Jaillet, Madeleine, Mailleux, Arnaud, Quesnel, Christophe, Poté, Nicolas, Debray, Marie-Pierre, de Montmollin, Etienne, Neukirch, Catherine, Borie, Raphael, Taillé, Camille, Crestani, Bruno, Covid Cohort Study Group, French, Andréjak, Claire
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021, 321 (5), pp.L847-L858. ⟨10.1152/ajplung.00105.2021⟩
Increased blood fibrocytes are associated with a poor prognosis in fibrotic lung diseases. We aimed to determine whether the percentage of circulating fibrocytes could be predictive of severity and prognosis during coronavirus disease 2019 (COVID-19)
Autor:
Townsend Benard, Fei Peng, Donato A. Rivas, Adelino Sanchez Ramos da Silva, Roger A. Fielding, Lee M. Margolis
Publikováno v:
American Journal of Physiology-Cell Physiology
Understanding paradoxical responses to anabolic stimulation and identifying the mechanisms for this inconsistency in mobility-limited older adults may provide new targets for the treatment of sarcopenia. Our laboratory has discovered that dysregulati
Autor:
Yu-An Zhang, Johanne Pastor, Joshuah M Gagan, Orson W. Moe, Jianning Zhang, Connie C.W. Hsia, Khoa Cao, Taylor L. Davidson
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Normal lungs do not express α-Klotho (Klotho) protein but derive cytoprotection from circulating soluble Klotho. It is unclear whether chronic supranormal Klotho levels confer additional benefit. To address this, we tested the age-related effects of
Autor:
Estela Lorza-Gil, Jürgen Machann, Felicia Gerst, Martin Heni, Anja Moller, Morgana Barroso Oquendo, Dorothea Siegel-Axel, Hans-Ulrich Häring, Susanne Ullrich, Robert Wagner, Alfred Königsrainer, Falko Fend, Andreas L. Birkenfeld
Publikováno v:
Am. J. Physiol.-Cell Physiol. 320, C1000-C1012 (2021)
Obesity, especially visceral fat accumulation, increases the risk of type 2 diabetes (T2D). The purpose of this study was to investigate the impact of T2D on the pancreatic fat depot. Pancreatic fat pads from 17 partial pancreatectomized patients (PP
Autor:
Khodr Tello, Hossein Ardeschir Ghofrani, Friedrich Grimminger, István Vadász, Robert Naeije, Manuel J. Richter, Athiththan Yogeswaran, S Harth, Faeq Husain-Syed, Werner Seeger, Henning Gall, Ryan J. Tedford, Steven Hsu
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Right ventricular (RV) function determines outcome in pulmonary arterial hypertension (PAH). RV pressure-volume loops, the gold standard for measuring RV function, are difficult to analyze. Our aim was to investigate whether simple assessments of RV
Autor:
Caitlin MacRae, Cameron J. Mitchell, David Cameron-Smith, Randall F. D'Souza, Troy L. Merry, James F. Markworth, Chantal A. Pileggi, Vandre C. Figueiredo, Nina Zeng
Publikováno v:
American Journal of Physiology-Cell Physiology. 320:C591-C601
Disuse-induced muscle atrophy is accompanied by a blunted postprandial response of the mammalian target of rapamycin complex 1 (mTORC1) pathway. Conflicting observations exist as to whether postabsorptive mTORC1 pathway activation is also blunted by
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
We have previously reported that several patients with idiopathic pulmonary hypertension (PH) had different types of G6PD deficiency. However, the role of G6PD in PH is multifactorial because G6PD is involved in controlling oxidative stress, metaboli