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Autor:
Frank A. Dinenno, Matthew L. Racine, Gary J. Luckasen, Christopher M. Hearon, Janée D. Terwoord
Publikováno v:
J Appl Physiol (1985)
The vascular endothelium senses and integrates numerous inputs to regulate vascular tone. Recent evidence reveals complex signal processing within the endothelium, yet little is known about how endothelium-dependent stimuli interact to regulate blood
Publikováno v:
Journal of Applied Physiology. 130:17-25
Heterogeneous flow-mediated dilation (FMD) and low-flow-mediated constriction (L-FMC) responses have been reported between upper- and lower-limb arteries. Radial artery L-FMC, but not FMD, responses are blunted when endothelial-derived hyperpolarizin
Autor:
Karishma Lakhani, Jeffrey Gornbein, Roya Moheimani, Kevin Nguyen, Elizabeth Tran, Isabella Ruedisueli, Kacey P Haptonstall, Yasmine Choroomi, Holly R. Middlekauff
Publikováno v:
American journal of physiology. Heart and circulatory physiology, vol 319, iss 3
Am J Physiol Heart Circ Physiol
Am J Physiol Heart Circ Physiol
Tobacco cigarette (TC) smoking has never been lower in the United States, but electronic cigarette (EC) vaping has reached epidemic proportions among our youth. Endothelial dysfunction, as measured by flow-mediated vasodilation (FMD) is a predictor o
Autor:
Emily Burrage, Sarah Reppert, Paul D. Chantler, Eiman Aboaziza, I M Olfert, Josh Moore, Lance A. Hare, Eric E. Kelley, D Dakhlallah, W T Goldsmith, Amber Mills
Publikováno v:
Am J Physiol Heart Circ Physiol
Electronic cigarettes (E-cigs) have been promoted as harm-free or less risky than smoking, even for women during pregnancy. These claims are made largely on E-cig aerosol having fewer number of toxic chemicals compared with cigarette smoke. Given tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4561b10aa20120a4fc839231bdee3e3a
https://europepmc.org/articles/PMC8410118/
https://europepmc.org/articles/PMC8410118/
Autor:
Jay L. Zweier, Mohamed G Ewees, Tamer M. Abdelghany, Mahmoud S Eid, Mohamed A. El-Mahdy, Elsayed M Mahgoup
Publikováno v:
Am J Physiol Heart Circ Physiol
Electronic cigarette (e-cig) vaping (ECV) has been proposed as a safer alternative to tobacco cigarette smoking (TCS); however, this remains controversial due to a lack of long-term comparative studies. Therefore, we developed a chronic mouse exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ee3a400cea935be84f3240036e9658
https://europepmc.org/articles/PMC8163641/
https://europepmc.org/articles/PMC8163641/
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 314:H343-H349
Psoriasis is an independent risk factor for cardiovascular disease; however, the underlying mechanisms are not fully understood. Deficits in conduit arterial function are evident in patients with psoriasis, but potential impairments in microcirculato
Autor:
Guido Lastra, Brady J. Barron, James R. Sowers, Melvin R. Hayden, Camila Manrique, Jaume Padilla, Guanghong Jia, Brett Niles, Annayya R. Aroor
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 313:R67-R77
Consumption of a high-fat, high-fructose diet [Western diet (WD)] promotes vascular stiffness, a critical factor in the development of cardiovascular disease (CVD). Obese and diabetic women exhibit greater arterial stiffness than men, which contribut
Autor:
Philip N. Ainslie, Alexander B. Hansen, Michael M. Tymko, James D. Anholm, Christopher K. Willie, Ryan L. Hoiland, Connor A. Howe, Daniela Flück, Mike Stembridge, Kevin W. Wildfong, Mathew G. Rieger, Prajan Subedi, Anthony R. Bain
Publikováno v:
Journal of Applied Physiology. 122:795-808
Hypoxia increases cerebral blood flow (CBF) with the underlying signaling processes potentially including adenosine. A randomized, double-blinded, and placebo-controlled design, was implemented to determine if adenosine receptor antagonism (theophyll
Currently, dual- or triple-drug combinations comprising different vasodilators are the mainstay for the treatment of pulmonary arterial hypertension (PAH). However, the patient outcome continues to be disappointing because the existing combination th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaf1bf32a33c6ec7adac8d3ccf2f15e
https://europepmc.org/articles/PMC6383494/
https://europepmc.org/articles/PMC6383494/
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1695-H1701
Chronic kidney disease is a known complication of hematopoietic stem cell transplant (HSCT) and can be caused by irradiation at the time of the HSCT. In our rat model there is a 6- to 8-wk latent period after irradiation that leads to the development