Zobrazeno 1 - 10
of 248
pro vyhledávání: ''
Autor:
Daniel W. Shi, Yu Fu, Yanbo Tang, Xuan Zheng Shi, Shrilakshmi Hegde, Li Yen Mae Huang, You-Min Lin
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Constipation and abdominal pain are commonly encountered in opioid-induced bowel dysfunction (OBD). The underlying mechanisms are incompletely understood, and treatments are not satisfactory. As patients with OBD often have fecal retention, we aimed
Autor:
Caroline A McCormick, Harikrishnan Parameswaran, Suzanne E Stasiak, Ralston D Augspurg, Jeffrey W. Ruberti, Ryan R. Jamieson, Samuel R. Polio
Publikováno v:
J Appl Physiol (1985)
The current therapeutic approach to asthma focuses exclusively on targeting inflammation and reducing airway smooth muscle force to prevent the recurrence of symptoms. However, even when inflammation is brought under control, airways in an asthmatic
Autor:
Nicholas D. Fried, Jason D. Gardner, Tamara M. Morris, Eric Lazartigues, Xinping Yue, Anna Whitehead
Publikováno v:
Am J Physiol Heart Circ Physiol
Use of electronic cigarettes is rapidly increasing among youth and young adults, but little is known regarding the long-term cardiopulmonary health impacts of these nicotine-containing devices. Our group has previously demonstrated that chronic, inha
Publikováno v:
American Journal of Physiology-Cell Physiology. 320:C155-C161
The innate and adaptive immune systems play an important role in the development of cardiac diseases. Therefore, it has become critical to identify molecules that can modulate inflammation in the injured heart. In this regard, activation of the choli
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Antenatal steroids (ANS) accelerate fetal lung maturation and reduce the incidence of respiratory distress syndrome. However, sex specificity, i.e., being less effective in males, and potential long-term neurodevelopmental sequelae, particularly with
Autor:
Christophe Langouet-Astrie, James F. Colbert, Eric P. Schmidt, Wells B. LaRivière, Joseph A. Hippensteel
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every country in the world. Despite an unprecedented focus of scientific investi
Autor:
Ming Lei, Richard Vickers, Kyongbum Lee, Karin Yanagi, David R. Snydman, Nicholas Alden, Anne Kane, Cheleste M. Thorpe, Xi Qian
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology
Antibiotic treatment is a standard therapy for Clostridioides difficile infection, but dysbiosis of the gut microbiota due to antibiotic exposure is also a major risk factor for the disease. Following an initial episode of C. difficile infection, a r
Autor:
Leiting Wei, Qiao Bingke, Songhong Jiang, Chen Xuequn, Zhou Le, Yang Zhou, Ma Xingyu, Yuzhu Han, Jianjun Zhao, Liu Anfang, Qian Shen
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 318:E817-E829
Studies have shown that there are differences between the sexes regarding to the occurrence and development of liver diseases, which may be associated with sex hormones. However, the mechanisms behind it are largely unknown. In this study, we first i
Autor:
Marcelino de Souza Durão, Daniela Mendes Chiloff, Miguel Angelo Goes, Abolfazl Zarjou, Christopher D. Porada, Graça Almeida-Porada, Nadia El-Akabawy, Danilo Candido de Almeida, Sunil George, Alshaimaa Mahmoud Morsi, Maria Eugênia Fernandes Canziani, Maria Aparecida Dalboni
Publikováno v:
Am J Physiol Renal Physiol
Serum soluble Fas (sFas) levels are associated with erythropoietin (Epo) hyporesponsiveness in patients with chronic kidney disease (CKD). Whether sFas could predict the need for erythropoiesis-stimulating agent (ESA) usage and its influence in eryth
Autor:
Sarah N. Framnes-DeBoer, Randy J. Seeley, Darleen A. Sandoval, Ellen Bakke, Deanna M. Arble, Hannah Peterson, Suma Yalamanchili
Publikováno v:
Am J Physiol Endocrinol Metab
Bromocriptine, a dopamine D2 receptor agonist originally used for the treatment of hyperprolactinemia, is largely successful in reducing hyperglycemia and improving glucose tolerance in type 2 diabetics. However, the mechanism behind bromocriptine’