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Publikováno v:
Journal of Applied Physiology. 131:1460-1468
This study examined the effect of aerobic exercise with and without blood flow restriction (BFR) on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid systems. In a randomized crossover design, pain-free individuals performed 20 m
Autor:
Urs A. Leuenberger, Jonathan Luck, Jian Cui, Cheryl Blaha, Lawrence I. Sinoway, Takuto Hamaoka
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
The effects of nitroglycerin (glyceryl trinitrate, GTN) on baroreflex sensitivity (BRS) are incompletely understood. Moreover, there are no reports evaluating the acute responses in both the sympathetic BRS (SBRS) and the cardiovagal BRS (CBRS) to th
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 321:G367-G377
Remifentanil impairs swallowing, and disturbed accommodation to bolus volume may be one of the underlying causes. It is not fully understood whether remifentanil-induced swallowing dysfunction is mediated by peripheral or central mechanisms. So, this
Publikováno v:
Physiology
The hypoxia-hypoxia-inducible factor (HIF)-1α-A2-adenosinergic pathway protects tissues from inflammatory damage during antipathogen immune responses. The elimination of this physiological tissue-protecting mechanism by supplemental oxygenation may
Autor:
Thomas Christian Bonne, Tomas Ganz, Grace Jung, Andreas Breenfeldt Andersen, Elizabeta Nemeth, Nikolai Baastrup Nordsborg, Jesús R. Huertas, Jacob Bejder, Niels Vidiendal Olsen
Publikováno v:
Breenfeldt Andersen, A, Bonne, T C, Bejder, J, Jung, G, Ganz, T, Nemeth, E, Olsen, N V, Rodriguez Huertas, J & Nordsborg, N B 2021, ' Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 321, no. 2, pp. R152-R161 . https://doi.org/10.1152/ajpregu.00070.2021
Am J Physiol Regul Integr Comp Physiol
Am J Physiol Regul Integr Comp Physiol
Current markers of iron deficiency (ID) such as ferritin and hemoglobin have shortcomings, and hepcidin and erythroferrone (ERFE) could be of clinical relevance in relation to early assessment of ID. Here, we evaluate whether exposure to altitude-ind
Autor:
Frank A. Dinenno, Matthew L. Racine, Gary J. Luckasen, Christopher M. Hearon, Janée D. Terwoord
Publikováno v:
J Appl Physiol (1985)
The vascular endothelium senses and integrates numerous inputs to regulate vascular tone. Recent evidence reveals complex signal processing within the endothelium, yet little is known about how endothelium-dependent stimuli interact to regulate blood
Publikováno v:
Jessen, S, Eibye, K, Christensen, P M, Hostrup, M & Bangsbo, J 2021, ' No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men ', Journal of Applied Physiology, vol. 131, no. 1, pp. 238-249 . https://doi.org/10.1152/japplphysiol.00108.2021
We investigated the effect of caffeine and acetaminophen on power output during a 6-min performance-test, peripheral fatigue, and muscle protein kinase A (PKA) substrate-phosphorylation. Fourteen men (age(mean±SD): 26±6 years; V̇O2max: 63.9±5.0 m
Autor:
Alejandro González-Candia, María José García-Celma, Aitor Caballero-Román, Emilio A. Herrera, Esteban G. Figueroa, Cristina Fornaguera, Elvira Escribano-Ferrer
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Stroke is the second leading cause of death worldwide, estimated that one-sixth of the world population will suffer it once in their life. The most common type of this medical condition is the ischemic stroke (IS), produced by a thrombotic or embolic
Autor:
Yuzhi Chen, Charlotte A Love, Jason D. Surratt, Camille Ehre, Elise Hickman, Yael-Natalie Escobar, Meghan E. Rebuli, Cameron B. Morrison, Ilona Jaspers
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
In the United States, millions of adults use electronic cigarettes (e-cigs), and a majority of these users are former or current cigarette smokers. It is unclear, whether prior smoking status affects biological responses induced by e-cigs. In this st
Autor:
Daniel W. Shi, Yu Fu, Yanbo Tang, Xuan Zheng Shi, Shrilakshmi Hegde, Li Yen Mae Huang, You-Min Lin
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Constipation and abdominal pain are commonly encountered in opioid-induced bowel dysfunction (OBD). The underlying mechanisms are incompletely understood, and treatments are not satisfactory. As patients with OBD often have fecal retention, we aimed