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Autor:
Philip N. Ainslie, Alexander B. Hansen, Michael M. Tymko, James D. Anholm, Christopher K. Willie, Ryan L. Hoiland, Connor A. Howe, Daniela Flück, Mike Stembridge, Kevin W. Wildfong, Mathew G. Rieger, Prajan Subedi, Anthony R. Bain
Publikováno v:
Journal of Applied Physiology. 122:795-808
Hypoxia increases cerebral blood flow (CBF) with the underlying signaling processes potentially including adenosine. A randomized, double-blinded, and placebo-controlled design, was implemented to determine if adenosine receptor antagonism (theophyll
Autor:
Richard Sotornik, Julie Ménard, Pascal Brassard, Jean-Patrice Baillargeon, Jean-Luc Ardilouze, Maude Gagnon-Auger
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 309:E55-E62
Acetylcholine (Ach) has vasodilatory actions. However, data are conflicting about the role of Ach in regulating blood flow in subcutaneous adipose tissue (ATBF). This may be related to inaccurate ATBF recording or to the responder/nonresponder (R/NR)
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 302:R150-R158
We hypothesized that vascular nitric oxide synthase (NOS) function and expression is differentially regulated in adult Dahl salt-sensitive rats maintained on Teklad or American Institutes of Nutrition (AIN)-76A standard chow diets from 3 to 16 wk old
Autor:
Annick Drouin, Jean-Claude Tardif, Nathalie Thorin-Trescases, Marc-Antoine Gillis, Christine Des Rosiers, Eric Thorin, Virginie Bolduc, Natacha Duquette, Isabelle Frayne-Robillard
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H2081-H2092
The cardiac cycle imposes a mechanical stress that dilates elastic carotid arteries, while shear stress largely contributes to the endothelium-dependent dilation of downstream cerebral arteries. In the presence of dyslipidemia, carotid arteries stiff
Autor:
Darren P. Casey, Michael J. Joyner
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H261-H268
We tested the hypothesis that 1) prostaglandins (PGs) contribute to compensatory vasodilation in contracting human forearm subjected to acute hypoperfusion, and 2) the combined inhibition of PGs and nitric oxide would attenuate the compensatory vasod
Autor:
Christopher T. Minson, Jessica R. Meendering, Britta N. Torgrimson, Paul F. Kaplan, Nicole P. Miller
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H1630-H1637
Medroxyprogesterone acetate (MPA) is widely known for its use in combination hormone therapy for postmenopausal women. However, MPA is also commonly used in young women for contraception and treatment of a number of gynecological conditions. Despite
Autor:
Camilla Alexanderson, Göran Bergström, Agneta Holmäng, Ole Skøtt, Maria E. Johansson, Irene J. Andersson
Publikováno v:
Johansson, M E, Andersson, I J, Alexanderson, C, Skøtt, O, Holmang, A & Bergstrom, G 2008, ' Hyperinsulinemic rats are normotensive but sensitized to angiotensin II ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 294, pp. R1240-R1247 . https://doi.org/10.1152/ajpregu.00493.2007
The effect of insulin on blood pressure (BP) is debated, and an involvement of an activated renin-angiotensin aldosterone system (RAAS) has been suggested. We studied the effect of chronic insulin infusion on telemetry BP and assessed sympathetic act
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H1216-H1225
Although the hydraulic work generated by the left ventricle (LV) is not disputed, how the work was dissipated through the systemic circulation is still subject to interpretation. Recently, we proposed that the systemic circulation should be considere
Autor:
Cynthia Hogeman, Urs A. Leuenberger, Patrick M. McQuillan, Latoya Linton-Frazier, Raman Moradkhan, Andrea Leuenberger
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H2289-H2295
The extent to which sympathetic nerve activity restrains metabolic vasodilation in skeletal muscle remains unclear. We determined forearm blood flow (FBF; ultrasound/Doppler) and vascular conductance (FVC) responses to 10 min of ischemia [reactive hy
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293:R1393-R1399
Digestion of large meals in pythons produces substantial increases in heart rate and cardiac output, as well as a dilation of the mesenteric vascular bed leading to intestinal hyperemia, but the mediators of these effects are unknown. Bolus intra-art