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Publikováno v:
Journal of Applied Physiology. 131:1460-1468
This study examined the effect of aerobic exercise with and without blood flow restriction (BFR) on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid systems. In a randomized crossover design, pain-free individuals performed 20 m
Autor:
Thomas Christian Bonne, Tomas Ganz, Grace Jung, Andreas Breenfeldt Andersen, Elizabeta Nemeth, Nikolai Baastrup Nordsborg, Jesús R. Huertas, Jacob Bejder, Niels Vidiendal Olsen
Publikováno v:
Breenfeldt Andersen, A, Bonne, T C, Bejder, J, Jung, G, Ganz, T, Nemeth, E, Olsen, N V, Rodriguez Huertas, J & Nordsborg, N B 2021, ' Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 321, no. 2, pp. R152-R161 . https://doi.org/10.1152/ajpregu.00070.2021
Am J Physiol Regul Integr Comp Physiol
Am J Physiol Regul Integr Comp Physiol
Current markers of iron deficiency (ID) such as ferritin and hemoglobin have shortcomings, and hepcidin and erythroferrone (ERFE) could be of clinical relevance in relation to early assessment of ID. Here, we evaluate whether exposure to altitude-ind
Autor:
Frank A. Dinenno, Matthew L. Racine, Gary J. Luckasen, Christopher M. Hearon, Janée D. Terwoord
Publikováno v:
J Appl Physiol (1985)
The vascular endothelium senses and integrates numerous inputs to regulate vascular tone. Recent evidence reveals complex signal processing within the endothelium, yet little is known about how endothelium-dependent stimuli interact to regulate blood
Publikováno v:
Jessen, S, Eibye, K, Christensen, P M, Hostrup, M & Bangsbo, J 2021, ' No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men ', Journal of Applied Physiology, vol. 131, no. 1, pp. 238-249 . https://doi.org/10.1152/japplphysiol.00108.2021
We investigated the effect of caffeine and acetaminophen on power output during a 6-min performance-test, peripheral fatigue, and muscle protein kinase A (PKA) substrate-phosphorylation. Fourteen men (age(mean±SD): 26±6 years; V̇O2max: 63.9±5.0 m
Publikováno v:
Journal of Applied Physiology. 130:1955-1960
Few minutes of hypoxic exposure stabilizes hypoxia-inducible factor-1α, resulting in erythropoietin (EPO) gene transcription and production. The objective of this study was to identify the shortest intermittent hypoxia protocol necessary to increase
Autor:
Alessia Fornoni, Leopoldo Raij, Surya V. Seshan, Evren U. Azeloglu, Gabriel Rezonzew, Ming Sheng Zhou, Alecia N. Muwonge, Run-Xia Tian, Edgar A. Jaimes, Sandra Merscher, Mohammed Siddiqui, Nicholas J. Wong
Publikováno v:
Am J Physiol Renal Physiol
Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Besides glycemic and blood pressure control, environmental factors such as cigarette smoking (CS) adversely affect the progression of DN. The effects of CS on DN progression
Publikováno v:
Journal of Applied Physiology. 130:17-25
Heterogeneous flow-mediated dilation (FMD) and low-flow-mediated constriction (L-FMC) responses have been reported between upper- and lower-limb arteries. Radial artery L-FMC, but not FMD, responses are blunted when endothelial-derived hyperpolarizin
Autor:
Andrea Gogos, Nadia Hale, Nadine Brew, S A Ingelse, Flora Y. Wong, David W. Walker, K L Shepherd, M. van den Buuse
Publikováno v:
Journal of Applied Physiology. 129:1431-1438
Dopamine is often used to treat hypotension in preterm infants who are at risk of hypoxic-ischemic (HI) brain injury due to cerebral hypoperfusion and impaired autoregulation. There is evidence that systemically administered dopamine crosses the pret
Publikováno v:
American Journal of Physiology-Renal Physiology. 319:F618-F623
Vascular calcification is a known complication of chronic kidney disease (CKD). The prevalence of vascular calcification in patients with non-dialysis-dependent CKD stages 3–5 has been shown to be as high as 79% ( 20 ). Vascular calcification has b
Autor:
Hongmei Qu, Raouf A. Khalil
Publikováno v:
Am J Physiol Heart Circ Physiol
Preeclampsia is a major complication of pregnancy manifested as hypertension and often intrauterine growth restriction, but the underlying pathophysiological mechanisms are unclear. Predisposing genetic and environmental factors cause placental malad